============================================================================================================= Network simulations of self-sustained activity in networks of adaptive exponential integrate and fire neurons ============================================================================================================= Demo files implemented using both NEURON and PyNN. The top level folder (the folder with this README) python files will work with PyNN version 0.8 and the python files in the prevPyNN subfolder will work with PyNN version 0.7 demo_cx-lts ----------- Simulations of self-sustained AI states in a small N=500 network of excitatory and inhibitory neurons, described by Adaptive Exponential (Brette-Gerstner-Izhikevich) type neurons with exponential approach to threshold. The connectivity is random and there is a small proportion (5%) of LTS cells among the excitatory neurons. This simulation reproduces Fig. 7 of the paper below. demo_cx_up-down --------------- Simulations of Up-Down states in a two-layer cortical network, with one N=2000 network and a smaller N=500 network. Both networks have excitatory and inhibitory neurons described by Adaptative Exponential (Brette-Gerstner-Izhikevich) type neurons with exponential approach to threshold. The connectivity is random within each network as well as between them. In the N=500 network, there is a small proportion (5%) of LTS cells among the excitatory neurons. This simulation reproduces Fig. 13 of the paper below. See details in the following article: Destexhe, A. Self-sustained asynchronous irregular states and Up/Down states in thalamic, cortical and thalamocortical networks of nonlinear integrate-and-fire neurons. Journal of Computational Neuroscience 27: 493-506, 2009. arXiv preprint: http://arxiv.org/abs/0809.0654 Original NEURON implementation by Alain Destexhe destexhe@unic.cnrs-gif.fr http://cns.iaf.cnrs-gif.fr Converted to PyNN by Andrew Davison davison@unic.cnrs-gif.fr and Lyle Muller lyle.e.muller@gmail.com Usage (NEURON version): nrnivmodl nrngui <file.oc> Usage (Python version): python <file.py> <simulator> where <file.py> is one of the demo files, and <simulator> is one of neuron, nest, pcsim, brian, facets_hardware2, etc...