//=================================================== // Channels for minimum HH models in Popischill 2008 // modified from genesis/scripts/neuron/channels.g // note: used l'hopital rule on tabchannel defs // remove singularity to prevent runtime error //=================================================== float ENa = 0.050 float V_T = -65e-3 //================================================= // NA CHANNEL (Traub, Miles 1991) //================================================= function make_Na create tabchannel Na setfield ^ Ek {ENa} Gbar {500} Xpower 3 Ypower 1 Zpower 0 int xdivs=5000 float xmin=-0.100, xmax=0.050, dx={(xmax-xmin)/xdivs} call Na TABCREATE X {xdivs} {xmin} {xmax} call Na TABCREATE Y {xdivs} {xmin} {xmax} float valX_A, valX_B, valY_A, valY_B, Vm int i for (i=0; i<={xdivs}; i=i+1) Vm = xmin + i*dx valX_A = -0.32e6*(Vm-V_T-13e-3)/({exp {(Vm-V_T-13e-3)/-4e-3}}-1) valX_B = 0.28e6*(Vm-V_T-40e-3)/({exp {(Vm-V_T-40e-3)/5e-3}}-1) valY_A = 0.128e3*{exp {(Vm-V_T-17e-3)/-18e-3}} valY_B = 4e3/({exp {(Vm-V_T-40e-3)/-5e-3}}+1) if ({({exp {(Vm-V_T-13e-3)/-4e-3}}-1)}==0) valX_A = -0.32e6/(1/-4e-3*{exp {(Vm-V_T-13e-3)/-4e-3}}) end if ({({exp {(Vm-V_T-40e-3)/5e-3}}-1)}==0) valX_B = 0.28e6/(1/5e-3*{exp {(Vm-V_T-40e-3)/5e-3}}) end setfield Na X_A->table[{i}] {valX_A} X_B->table[{i}] {valX_B} setfield Na Y_A->table[{i}] {valY_A} Y_B->table[{i}] {valY_B} end tweakalpha Na X tweakalpha Na Y end // make channel make_Na