/**
* Activation
*/
function Kd_ainf(Vm)
float Vm
float v = 1.0e3 * {Vm} /* Volt to Millivolt. */
return {1.0 / {1.0 + {exp {{{-50.0} - {v}} / {20.0}}}}}
end
/**
* Inactivation.
*/
function Kd_binf(Vm)
float Vm
float v = 1.0e3 * {Vm} /* Volt to Millivolt. */
return {1.0 / {1.0 + {exp {{{-70.0} - {v}} / {-6.0}}}}}
end
function make_Kd_chan
str path = "Kd_chan"
float Erev = -0.090 /* reversal potential of sodium */
float xmin = -0.100 /* minimum voltage we will see in the simulation */
float xmax = 0.050 /* maximum voltage we will see in the simulation */
float step = 0.005 /* use a 5mV step size */
int xdivs = 30 /* the number of divisions between -0.1 and 0.05 */
int i
create tabchannel {path}
/* make the table for the activation with a range of -100mV - +50mV
* with an entry for ever 5mV
*/
call {path} TABCREATE X {xdivs} {xmin} {xmax}
call {path} TABCREATE Y {xdivs} {xmin} {xmax}
/* set the tau and m_inf for the activation and inactivation */
for(i = 0; i < {xdivs} + 1; i = i + 1)
setfield {path} X_A->table[{i}] {0.002}
setfield {path} X_B->table[{i}] {Kd_ainf {{xmin} + {i * {step}}}}
setfield {path} Y_A->table[{i}] {0.150}
setfield {path} Y_B->table[{i}] {Kd_binf {{xmin} + {i * {step}}}}
end
setfield {path} Ek {Erev} Xpower 3 Ypower 1
tweaktau {path} X
tweaktau {path} Y
call {path} TABFILL X 3000 0
call {path} TABFILL Y 3000 0
setfield {path} X_A->calc_mode 0 X_B->calc_mode 0
setfield {path} Y_A->calc_mode 0 Y_B->calc_mode 0
end