// Geometry-induced features of current transfer in neuronal dendrites with tonically activated conductances
// Sergey M. Korogod, Irina B. Kulagina
// Biol. Cybern. 79, 231-240 (1998)
objectvar TRGraph
objectvar Stim
// define membrane mechanisms
proc SetMembrane() {
strdef OutLine
OutLine = "Soma {insert PasSA}"
execute1(OutLine)
for i=0, 2 {
sprint(OutLine, "Dendrite[%d] {insert PasD gs_PasD = 0.0}", i)
execute1(OutLine)
}
} // SetMembrane()
func CalcT() { local T
T = (v($1) - erev_PasD($1)) / 10
return T
} // CalcT()
// make graphics for Fig.4. D (asymmetric)
proc MakeTRGraph() {
strdef OutLine
TRGraph = new Graph(0)
TRGraph.xaxis()
TRGraph.yaxis()
RRGraph = new RangeVarPlot("CalcT($1)")
OutLine = "Dendrite[0] RRGraph.begin(0) Dendrite[1] RRGraph.end(1)"
execute1(OutLine)
TRGraph.addobject(RRGraph, 1, 1, 1, 1)
RRGraph = new RangeVarPlot("CalcT($1)")
OutLine = "Dendrite[0] RRGraph.begin(0) Dendrite[2] RRGraph.end(1)"
execute1(OutLine)
TRGraph.addobject(RRGraph, 1, 1, 1, 1)
TRGraph.size(0, 800, 0.5, 1)
TRGraph.view(0, 0.5, 800, 0.5, 360, 269, 385, 250)
TRGraph.label(0.5, 1, "D", 2, 1, 0, 1, 1)
TRGraph.label(0.05, 1, "T(x)", 2, 1, 0, 1, 1)
TRGraph.label(0.9, 0.15, "um", 2, 1, 0, 1, 1)
flush_list.append(TRGraph)
TRGraph.save_name("flush_list.")
objectvar RRGraph
} // MakeTRGraph()
proc Destroy() {
objectvar Stim
TRGraph.unmap()
} // Destroy()
proc MainExec() {
GetModelTopology(5)
SetMembrane()
OutLine = "access Soma"
execute1(OutLine)
OutLine = "Soma Stim = new IClamp(0.75)"
execute1(OutLine)
OutLine = "Stim.del = 0"
execute1(OutLine)
OutLine = "Stim.dur = 50"
execute1(OutLine)
OutLine = "Stim.amp = 0.169"
execute1(OutLine)
tstop = 50
MakeTRGraph()
} // MainExec()
MainExec()