COMMENT
Modified from Michael Hines SpikeGenerator by Elena Saftenku, 2001
ENDCOMMENT
NEURON {
POINT_PROCESS SpGen2
RANGE y, t01,t02
RANGE fast_freq, slow_freq, APinburst, startbursting, endbursting
RANGE noise,delay
}
PARAMETER {
t01=20 (ms)
t02=420000 (ms)
fast_freq = 100 (/s)
slow_freq = 4 (/s)
APinburst = 10 : burst length (# spikes)
startbursting = 2000 (ms) : start of first interburst interval
endbursting = 3000 (ms) : time to stop bursting
noise = 0 : amount of randomeaness (0.0 - 1.0)
}
ASSIGNED {
fast_invl (ms)
slow_invl (ms)
y
burst
event (ms)
burst_off (ms)
burst_on (ms)
on
}
PROCEDURE seed(x) {
set_seed(x)
}
INITIAL {
on = 0
y = -70
endbursting = endbursting -1e-6
if (slow_freq != 0.) {slow_invl= (1/slow_freq )*(1000)}
if (fast_freq != 0.) {fast_invl= (1/fast_freq )*(1000) }
burst = 1
if (t01>0) {
event= t01
net_send (event,4)}
if (t02>0) {
event= t02
net_send (event,4)}
if (startbursting>=0 && APinburst >0 ) {
event = startbursting
net_send(event, 3)
}
}
FUNCTION interval(mean (ms)) (ms) {
if (mean <= 0.) {
mean = .01 (ms)
}
if (noise == 0) {
interval = mean
}else{
interval = (1. - noise)*mean + noise*mean*exprand(1)
}
}
PROCEDURE event_time() {
if (slow_freq == 0 || (burst != 0. && APinburst > 1)) {
event = event + interval(fast_invl)
if (slow_freq > 0 && event > burst_on + burst_off) {
burst = 0.
}
}else{
burst = 1.
: if slow_invl from beginning of burst to beginning of burst
event = event + interval(slow_invl - (APinburst-1)*fast_invl)
: use following if slow_invl is interburst interval
:event = event + interval(slow_invl)
burst_on = event
burst_off = interval((APinburst - 1)*fast_invl)-1e-6
}
if (event > endbursting) {
on = 0
}
}
NET_RECEIVE (w) {
:printf("Pregen receive t=%g flag=%g\n", t, flag)
if (flag == 3){
if (on == 0){
on =1
event = t
burst_on = event
burst_off = interval((APinburst - 1)*fast_invl)-1e-6
net_send (0,1)
} }
if (flag == 4)
{
if (on == 0) {
on = 1
event = t
net_send (0,1)}}
if (flag == 1 && on == 1) {
y = 20
net_event(t)
if (t>= startbursting && t<= endbursting)
{
event_time()
net_send(event - t, 1)
} else {on=0 }
net_send(.1, 2)
}
if (flag == 2) {
y = -70
}
}