# Ermentrout 1998 type I oscillator p gl=.2,gkdr=80,gna=80 p iapp=0.67 p C=1. p amphi=.32,amhalf=-54,amwidth=4 p bmphi=.28,bmhalf=-27,bmwidth=5 p ahphi=.128,ahhalf=-50,ahwidth=18 p bhphi=4,bhhalf=-27,bhwidth=5 p anphi=.032,anhalf=-52,anwidth=5 p bnphi=.5,bnhalf=-57,bnwidth=40 # functions am(v)=amphi*(v-amhalf)/(1-exp(-(v-amhalf)/amwidth)) bm(v)=bmphi*(v-bmhalf)/(exp((v-bmhalf)/bmwidth)-1) ah(v)=ahphi*exp(-(v-ahhalf)/ahwidth) bh(v)=bhphi/(1+exp(-(v-bhhalf)/bhwidth)) an(v)=anphi*(v-anhalf)/(1-exp(-(v-anhalf)/anwidth)) bn(v)=bnphi*exp(-(v-bnhalf)/bnwidth) Isyn(y,V)=gsyn*y*(V-Esyn) #currents ina(v,m,h)=gna*m^3*h*(v-Vna) ikdr(v,n)=gkdr*n^4*(v-Vk) il(v)=gl*(v-Vl) #diff. equ. v1'=(iapp-(ina(v1,m1,ha)+ikdr(v1,n1)+il(v1))+eps*(ua1-v1)/dx-p0*Isyn(y2,v1))/C v2'=(iapp-(ina(v2,m2,hb)+ikdr(v2,n2)+il(v2))+eps*(ub1-v2)/dx-p0*Isyn(y1,v2))/C m1'=am(v1)*(1-m1)-bm(v1)*m1 m2'=am(v2)*(1-m2)-bm(v2)*m2 n1'=an(v1)*(1-n1)-bn(v1)*n1 n2'=an(v2)*(1-n2)-bn(v2)*n2 ha'=ah(v1)*(1-ha)-bh(v1)*ha hb'=ah(v2)*(1-hb)-bh(v2)*hb ## synapse par taur=1,taud=3,thresh=-30, gsyn=1 Esyn=0 x1'=(-x1+.5*(1+tanh((v1-thresh)/3.0)))/taur x2'=(-x2+.5*(1+tanh((v2-thresh)/3.0)))/taur y1'=(-y1+x1)/taud y2'=(-y2+x2)/taud init x1=0,y1=0,x2=0,y2=0 par Vna=50,Vk=-100,Vl=-67,Vh=-65,Vrh=-40,Vsh=6,gld=0.1,gh=0.02,tauh=400 hinf(V)=1/(1+exp((V-Vh)/Vsh)) Ild(V)=V-Vl Ih(V,y)=gh*y*(V-Vrh)/gld ha[1..50]'=(hinf(ua[j])-ha[j])/tauh hb[1..50]'=(hinf(ub[j])-hb[j])/tauh # cable equation p p[0..50]=0 ua1'=((lambda/dx)^2*(ua2-2*ua1+v1)-Ild(ua1)-Ih(ua1,ha1)-p1*Isyn(y2,ua1)/gld)/tau ua[2..50]'= ((lambda/dx)^2*(ua[j+1]-2*ua[j]+ua[j-1])-Ild(ua[j])-Ih(ua[j],ha[j])-p[j]*Isyn(y2,ua[j])/gld)/tau ua51=(c1+b1*ua50/dx)/(a1+b1/dx) ub1'=((lambda/dx)^2*(ub2-2*ub1+v2)-Ild(ub1)-Ih(ub1,hb1)-p1*Isyn(y1,ub1)/gld)/tau ub[2..50]'= ((lambda/dx)^2*(ub[j+1]-2*ub[j]+ub[j-1])-Ild(ub[j])-Ih(ub[j],hb[j])-p[j]*Isyn(y1,ub[j])/gld)/tau ub51=(c1+b1*ub50/dx)/(a1+b1/dx) par lambda=1,tau=10,dx=.1,c1=0,a1=0,b1=1,c0=0,a0=0,b0=1,eps=.025 @ total=1000,dt=.05,xlo=0,xhi=1000,ylo=-100,yhi=50,bounds=1e6 i ua[1..50]=-60 i ha[1..50]=.1 i ub[1..50]=-60 i hb[1..50]=.1 d