This is a simulation of the electrical responses of three classes of granule cells of the olfactory bulb to synaptic inputs Start GENESIS simulator. On the command line type: Frontiers_granI.g =>to start the type I granule cell. Frontiers_granII.g =>to start the type II granule cell. Frontiers_granIII.g =>to start the type III granule cell. For Frontiers_gran(#).g you will see four panels: Panel 1: Control panel Panel 2: NMDA and AMPA receptor conductances in the stimulated spine Panel 3: Membrane potential in the soma and dendritic trunk Panel 4: full representation of the cell On the panel 1, click on the STIM button to start a simulation that stimulates the AMPA and NMDA receptors in the spines of the tip of the apical dendrites. You can also just inject a current in the soma by changing the Injection value (for instance 1e-10) and clicking on the RUN button. dt stands for the simulation time step, and Tmax stands for the maximum simulation time. On the panel 4, type the "<" and ">" keys to zoom out and in, and use the arrows to move the cell around. Use the key "p" to see the cell in perspective. Pseudocolor code represents the membrane potential of the compartments. "Hot" colors mean depolarization and "Cold" colors mean hyperpolarization.