COMMENT
//%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
//
// NOTICE OF COPYRIGHT AND OWNERSHIP OF SOFTWARE
//
// Copyright 2007, The University Of Pennsylvania
// School of Engineering & Applied Science.
// All rights reserved.
// For research use only; commercial use prohibited.
// Distribution without permission of Maciej T. Lazarewicz not permitted.
// mlazarew@seas.upenn.edu
//
//%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
This mode file is based on the paper:
Tort, A. B., Rotstein, H. G., Dugladze, T., et al. (2007). On the formation of gamma-coherent cell
assemblies by oriens lacunosum-moleculare interneurons in the hippocampus. Proc Natl Acad Sci U S A.
ENDCOMMENT
NEURON {
SUFFIX KdrPyrKop
USEION k WRITE ik
RANGE gmax
}
UNITS {
(mA) = (milliamp)
(mV) = (millivolt)
(mS) = (millisiemens)
}
PARAMETER {
gmax = 10.0 (mS/cm2)
ek = -90.0 (mV)
}
ASSIGNED {
v (mV)
ik (mA/cm2)
ninf (1)
taon (ms)
}
STATE { n }
INITIAL {
rates(v)
n = ninf
}
BREAKPOINT {
SOLVE states METHOD cnexp
ik = (1e-3) * gmax * n * (v-ek)
}
DERIVATIVE states {
rates(v)
n' = (ninf-n)/taon
}
PROCEDURE rates(v(mV)) { LOCAL an, bn
an = exp(-0.11(/mV)*(v-13.0))
bn = exp(-0.08(/mV)*(v-13.0))
ninf = 1.0/(1.0+an)
taon = max(2.0,50.0*bn/(1.0+an))*1.0(ms)
}
INCLUDE "aux_fun.inc"