TITLE K-A
: K-A current for Retinal Ganglion Cell from Benison et al (2001)
: M.Migliore Nov. 2001
NEURON {
SUFFIX kargc
USEION k READ ek WRITE ik
RANGE gbar
GLOBAL minf, hinf, mtau, htau
}
PARAMETER {
gbar = 0.010 (mho/cm2)
ek (mV) : must be explicitly def. in hoc
v (mV)
}
UNITS {
(mA) = (milliamp)
(mV) = (millivolt)
(pS) = (picosiemens)
(um) = (micron)
}
ASSIGNED {
ik (mA/cm2)
minf hinf
mtau (ms) htau (ms)
}
STATE { m h}
BREAKPOINT {
SOLVE states METHOD cnexp
ik = gbar*m*m*m*h * (v - ek)
}
INITIAL {
trates(v)
m=minf
h=hinf
}
DERIVATIVE states {
trates(v)
m' = (minf-m)/mtau
h' = (hinf-h)/htau
}
PROCEDURE trates(vm) {
LOCAL a, b
a = trap0(vm,-15,0.02,0.12)
b = 0.05*exp(-(vm+1)/30)
minf = a/(a+b)
mtau = 1/(a+b)
hinf = 1/(1+exp((vm+62)/6.35))
htau = 25
}
FUNCTION trap0(v,th,a,q) {
if (fabs(v-th) > 1e-6) {
trap0 = a * (v - th) / (1 - exp(-(v - th)*q))
} else {
trap0 = a / q
}
}