//genesis // // cell.p - template neuron prototype // // Reduction of the original model by Huss M, Lansner A, Wallen P, // El Manira A, Grillner S, Kotaleski JH. Roles of ionic currents // in lamprey CPG neurons: a modeling study. J Neurophysiol. 2007 // Apr;97(4):2696-711. Epub 2007 Feb 7 (ModelDB accession number 93319). // // The cell morphology is simplified in that the small adjacent membrane // compartments are lumped together to make longer cylinders. Cell membrane // of the simplified model contains 16 compartments: soma, axon initial // segment, 2 primary, 4 secondary and 8 tertiary dendrites. *relative *cartesian *asymmetric *set_compt_param EREST_ACT -0.078 *set_compt_param ELEAK -0.078 *set_global RA 1 *set_global RM 1 *set_global CM 0.01 *start_cell /library/soma soma none 0 0 20 20 Na 320 Ks 40 Kt 50 CaN 80 CaN_pool -1.25e5 KCaN 60 CaL 4 Na_pool -5e11 Na_slow_pool -3e9 KNa 50 KNa_slow 5.2 Glyc -1e-9 AMPA -0.25e-9 NMDA -0.12e-9 *makeproto /library/soma *start_cell /library/iseg iseg none 0 0 50 5 shNa 20000 Kt 6000 *makeproto /library/iseg *start_cell /library/prim_dend prim_dend none 90 0 0 5 Na 320 Ks 40 Kt 20 CaN 80 CaN_pool -1.25e5 KCaN 600 CaL 2 CaLVA 575 Na_pool -5e11 Na_slow_pool -3e9 KNa 150 KNa_slow 52 Glyc -1e-9 AMPA -0.25e-9 NMDA -0.12e-9 *makeproto /library/prim_dend *start_cell /library/secn_dend secn_dend none 150 0 0 3 Na 320 Ks 40 Kt 20 CaN 80 CaN_pool -1.25e5 KCaN 600 CaL 2 CaLVA 575 Na_pool -5e11 Na_slow_pool -3e9 KNa 150 KNa_slow 52 AMPA -0.25e-9 NMDA -0.12e-9 *makeproto /library/secn_dend *start_cell /library/tert_dend tert_dend none 240 0 0 2 Na 320 Ks 40 Kt 20 CaN 80 CaN_pool -1.25e5 KCaN 600 CaL 2 CaLVA 575 Na_pool -5e11 Na_slow_pool -3e9 KNa 150 KNa_slow 52 AMPA -0.25e-9 NMDA -0.12e-9 *makeproto /library/tert_dend *start_cell *compt /library/soma soma none 0 0 20 20 *compt /library/iseg iseg soma 0 0 50 5 *compt /library/prim_dend prox1 soma 90 0 0 5 prox2 soma 90 0 0 5 *compt /library/secn_dend medi1 prox1 150 0 0 3 medi2 prox1 150 0 0 3 medi3 prox2 150 0 0 3 medi4 prox2 150 0 0 3 *compt /library/tert_dend dist1 medi1 240 0 0 2 dist2 medi1 240 0 0 2 dist3 medi2 240 0 0 2 dist4 medi2 240 0 0 2 dist5 medi3 240 0 0 2 dist6 medi3 240 0 0 2 dist7 medi4 240 0 0 2 dist8 medi4 240 0 0 2