COMMENT
This file, dc.mod, implements the Direct current [Ca2+] sensor (D) from
Liu et al. 1998 (Activity dependent conductances)
Tom M Morse 20070807
Note that the transition rates depend on the Ca current, ica,
rather than on the membrane voltage.
ENDCOMMENT
NEURON {
SUFFIX D
USEION ca READ ica
RANGE D
}
UNITS {
(mA) = (milliamp)
}
PARAMETER {
G = 1 : p. 2312 after eqn 4
tau_M = 500 (ms) : p. 2313, table 2
Z_M = 3 : table 2 also
}
ASSIGNED {
Mbar (1) : Mbar and Hbar play the roles of m_inf, h_inf in
ica (mA/cm2)
D (1)
}
STATE { M (1)}
BREAKPOINT {
SOLVE states METHOD cnexp
D = G * M * M : note there is no driving force
}
INITIAL {
: assume that ica has been constant for a long time at startup
rates(ica)
M = Mbar
}
DERIVATIVE states {
rates(ica)
M' = (Mbar - M)/tau_M
}
PROCEDURE rates(ica (mA/cm2)) {
UNITSOFF
Mbar = 1/(1+exp( Z_M + 1e3*ica )) : units mA/cm2 is 1e-3*nA/nF when
: specific capacitance= 1 uF/cm2
UNITSON
}