// NetGUI default section. Artificial cells, if any, are located here.
create acell_home_
access acell_home_
//Network cell templates
// C_Cell
begintemplate C_Cell
public is_art
public init, topol, basic_shape, subsets, geom, memb
public synlist, x, y, z, position, connect2target
public soma
public all
objref synlist
proc init() {
topol()
subsets()
geom()
biophys()
geom_nseg()
synlist = new List()
synapses()
x = y = z = 0 // only change via position
}
create soma
proc topol() { local i
basic_shape()
}
proc basic_shape() {
soma {pt3dclear() pt3dadd(0, 0, 0, 1) pt3dadd(15, 0, 0, 1)}
}
objref all
proc subsets() { local i
objref all
all = new SectionList()
soma all.append()
}
proc geom() {
soma { /*area = 100 */ L = diam = 5.6419 }
}
external lambda_f
proc geom_nseg() {
soma area(.5) // make sure diam reflects 3d points
soma { nseg = 1 }
}
proc biophys() {
soma {
cm = 1
insert pas
g_pas = 0.0001
e_pas = -65
insert kdr
gmax_kdr = 0.009
insert naf
gmax_naf = 0.035
insert cur
amp_cur = 0.001
}
}
proc position() { local i
soma for i = 0, n3d()-1 {
pt3dchange(i, $1-x+x3d(i), $2-y+y3d(i), $3-z+z3d(i), diam3d(i))
}
x = $1 y = $2 z = $3
}
proc connect2target() { //$o1 target point process, $o2 returned NetCon
soma $o2 = new NetCon(&v(.5), $o1)
}
objref syn_
proc synapses() {
/* G0 */ soma syn_ = new GABAA(0.5) synlist.append(syn_)
}
func is_art() { return 0 }
endtemplate C_Cell
//Network specification interface
objref cells, nclist, netcon, nil
{cells = new List() nclist = new List()}
func cell_append() {cells.append($o1) $o1.position($2,$3,$4)
return cells.count - 1
}
func nc_append() {//srcindex, tarcelindex, synindex
if ($3 >= 0) {
cells.object($1).connect2target(cells.object($2).synlist.object($3),netcon)
netcon.weight = $4 netcon.delay = $5
}else{
cells.object($1).connect2target(cells.object($2).pp,netcon)
netcon.weight = $4 netcon.delay = $5
}
nclist.append(netcon)
netcon = nil
return nclist.count - 1
}
//Network instantiation
ncell = 100
variable_domain(&ncell, 2, 1e6)
proc makenet() {
nclist.remove_all
cells.remove_all
for i=0, ncell-1 { cell_append(new C_Cell(), i, 0, 0) }
if (1) {
for i=0, ncell-1 for j=0, ncell-1 if (i != j) {
nc_append(i, j, 0, 1e-4/(ncell - 1), 0)
}
}else{
for i=0, ncell-1 for j=0, ncell-1 {
nc_append(i, j, 0, 1e-4/ncell, 0)
}
}
for i=0, nclist.count-1 {
nclist.object(i).threshold = -5.67 // fitted to wang 1996
}
Cdur_GABAA = .4145 // fitted to wang 1996
}
makenet()