Note: This model only runs under UNIX (and linux) for the current version of neuron (5.2). Future versions of neuron for the mac and pc will be able to run this model. * simulation from: Lytton WW. Computer model of clonazepam's effect in thalamic slice. Neuroreport, 8:3339-3343, 1997. Figs. 3 (Fig3.gif; reticularis cells) and 4 (Fig4.gif; thalamocortical cells), p 3342 neurrep8:3339.pdf This simulation is very similar to the one published in the paper but is not identical due to variations among randomizers using supposedly identical algorithms. The original was run under Sun Solaris. The example files included here were produced under Intel Linux. I have chosen traces from the current runs that are very similar to those in the publication. However, these specific traces may not look identical if a different randomizer is used. I also graph all 64 traces from the network so that they can all be looked at and compared to the figure. * COMPILE and RUN: nrnivmodl RUN: $CPU/special init.hoc - * TO JUST LOOK AT PRE-SAVED DATA $CPU/special disp.hoc - to look at your newly run data later modify disp.hoc line 23 FROM showfiles("ctl.dat","czp.dat") TO showfiles("ctlnew.dat","czpnew.dat") 20110411 changed euler solve method to cnexp in IAHP_destexhe.mod ICAN_destexhe.mod as per "Integration methods for SOLVE statements" topic in the NEURON forum http://www.neuron.yale.edu/phpBB/viewtopic.php?f=28&t=592 -ModelDB Administrator Changelog --------- 2022-05: Updated MOD files to contain valid C++ and be compatible with the upcoming versions 8.2 and 9.0 of NEURON. 2022-12: IT2_huguenard.mod& IT_wang.mod: replace adams solver with runge (see https://github.com/ModelDBRepository/12631/pull/3 ) passiv.mod: drop INDEPENDENT block for v Required for upcoming NEURON 9.0.0 2023-04: Do not store pointers to RANGE variables. Required for upcoming NEURON 9.0.0.