:Comment :
:Reference : : Kole,Hallermann,and Stuart, J. Neurosci. 2006
NEURON {
SUFFIX IhHay
NONSPECIFIC_CURRENT ihcn
RANGE gIhbar, gIh, ihcn, ehcn, offma, sloma, tauma, offmb, slomb, taumb
}
UNITS {
(S) = (siemens)
(mV) = (millivolt)
(mA) = (milliamp)
}
PARAMETER {
gIhbar = 0.00001 (S/cm2)
ehcn = -45.0 (mV)
offma = -154.9 (mV)
sloma = 11.9 (mV)
tauma = 155.521 (ms)
offmb = 0.0 (mV)
slomb = 33.1 (mV)
taumb = 5.18135 (ms)
}
ASSIGNED {
v (mV)
ihcn (mA/cm2)
gIh (S/cm2)
mInf
mTau
mAlpha
mBeta
}
STATE {
m
}
BREAKPOINT {
SOLVE states METHOD cnexp
gIh = gIhbar*m
ihcn = gIh*(v-ehcn)
}
DERIVATIVE states {
rates()
m' = (mInf-m)/mTau
}
INITIAL{
rates()
m = mInf
}
PROCEDURE rates(){
UNITSOFF
if(v == offma){
v = v + 0.0001
}
mAlpha = -(offma-v)/tauma/(exp(-(offma-v)/sloma)-1)
mBeta = exp(-(offmb-v)/slomb)/taumb
mInf = mAlpha/(mAlpha + mBeta)
mTau = 1/(mAlpha + mBeta)
UNITSON
}