load_file("nrngui.hoc")
load_file("init.hoc")
secondorder=2
strdef figstr
proc fig1a() {
figstr="1A : standard parameter set"
standard()
prun()
}
proc fig1b() {
figstr="1B : cool to 6.3 DegC"
standard()
tstop = 5 tstop_changed()
celsius = 6.3
prun()
}
proc fig1c() {
figstr="1C : taper axon hillock"
standard()
taper()
prun()
}
proc fig1d() {
figstr="1D : extend HH in dendrite"
standard()
extrahh(100)
prun()
}
fig1a()
xpanel("Figures")
xvarlabel(figstr)
//xmenu("Fig 1")
xbutton("Figure 1A", "fig1a()")
xbutton("Figure 1B", "fig1b()")
xbutton("Figure 1C", "fig1c()")
xbutton("Figure 1D", "fig1d()")
//xmenu()
//xmenu("Figure 2")
xbutton("Figure 2A", "fig2a()")
xbutton("Figure 2B", "fig2b()")
//xmenu()
//xmenu("Fig 3")
xbutton("Figure 3A", "fig3a()")
xbutton("Figure 3B", "fig3b()")
xbutton("Figure 3C", "fig3c()")
//xmenu()
//xmenu("Fig 4")
xbutton("Figure 4A", "fig4a()")
xbutton("Figure 4B", "fig4b()")
xbutton("Figure 4C", "fig4c()")
//xmenu()
//xmenu("Fig 5")
xbutton("Figure 5A", "fig5a()")
xbutton("Figure 5B", "fig5b()")
xbutton("Figure 5C", "fig5c()")
xbutton("Figure 5D", "fig5d()")
xmenu()
xpanel(300,100)
proc fig2a() {
figstr="2A :extend HH to 500um"
standard()
extrahh(500)
prun()
}
proc fig2b() {
figstr="2B :increase HH density 5-fold"
standard()
forall if (ismembrane("hh")) { gnabar_hh *= 5 gkbar_hh *= 5 gl_hh *= 5 }
prun()
}
// paper states that 3c has amplitude of -0.15uA but at this location
// and duration, this model requires 700 nA
proc fig3a() {
figstr="3A : HH throughout dendrite"
standard()
extrahh(dend.L)
dend stimdef(2750/3400, .2, 700)
prun()
}
proc fig3b() {
figstr="3B : restrict HH to 300um in dendrite"
standard()
extrahh(300)
dend stimdef(2750/3400, .2, 700)
prun()
}
proc fig3c() {
figstr="3C : no HH in dendrite"
standard()
dend stimdef(2750/3400, .2, 700)
tstop = 5 tstop_changed()
prun()
}
proc fig4a() {
figstr="4A : stimulus amp=700 (not 150 nA)"
standard()
dend stimdef(2500/3400, .2, 700)
tstop = 5 tstop_changed()
prun()
}
proc fig4b() {
figstr="4B : stimulus amp=625 (not 133.5 nA)"
standard()
dend stimdef(2500/3400, .2, 625)
tstop = 5 tstop_changed()
prun()
}
proc fig4c() {
figstr="4C : stimulus amp=1400 (not 300 nA)"
standard()
dend stimdef(2500/3400, .2, 1400)
tstop = 5 tstop_changed()
prun()
}
proc fig5a() {
figstr="5A : taper axon hillock"
standard()
taper()
dend stimdef(2500/3400, .2, 700)
prun()
}
proc fig5b() {
figstr="5B : cool to 6.3 degC"
standard()
celsius=6.3
dend stimdef(2500/3400, .2, 700)
tstop = 5 tstop_changed()
prun()
}
proc fig5c() {
figstr="5C : 5*HH density"
standard()
forall if (ismembrane("hh")) { gnabar_hh *= 5 gkbar_hh *= 5 gl_hh *= 5 }
dend stimdef(2500/3400, .2, 700)
prun()
}
proc fig5d() {
figstr="5D : soma stimulated, amp=105"
standard()
soma stimdef(.25, .2, 105)
prun()
}