TITLE IA for horizontal cell
: Transient outward potassium current (IA) for horizontal cells
:
: Based on parameters of Aoyama et al. (2000)
INDEPENDENT {t FROM 0 TO 1 WITH 1 (ms)}
NEURON {
SUFFIX HzIA
USEION k READ ek WRITE ik
RANGE gbar
RANGE m_inf, h_inf
RANGE tau_m, tau_h
RANGE m_exp, h_exp
}
UNITS {
(mA) = (milliamp)
(mV) = (millivolt)
}
PARAMETER {
gbar = 1.4151e-04 (mho/cm2) : 15 nS total
}
STATE {
m h
}
ASSIGNED {
v (mV)
ek (mV)
ik (mA/cm2)
celsius (degC)
dt (ms)
m_inf
h_inf
tau_m
tau_h
m_exp
h_exp
tadj
}
BREAKPOINT {
SOLVE states
ik = gbar * m*m*m*h * (v - ek)
}
PROCEDURE states() {
: exact when v held constant
evaluate_fct(v)
m = m + m_exp * (m_inf - m)
h = h + h_exp * (h_inf - h)
}
UNITSOFF
INITIAL {
m = 0.030
h = 0.998
tadj = 3.0 ^ ((celsius-25)/10) : correction for physio temp
}
PROCEDURE evaluate_fct(v(mV)) { LOCAL a, b, v2
a = 2400 / ( 1 + exp( -(v-50)/28 ) )
b = 80 * exp( -v/36 )
tau_m = 1 / (a + b) /tadj
m_inf = a / (a + b)
a = exp( -v/60 )
b = 20 / ( exp( -(v+40)/5 ) + 1)
tau_h = 1 / (a + b) / tadj
h_inf = a / (a + b)
m_exp = 1 - exp(-dt/tau_m)
h_exp = 1 - exp(-dt/tau_h)
}
UNITSON