TITLE Cerebellum Golgi Cell Model
COMMENT
Calcium first order kinetics
Author: A. Fontana
Revised: 12.12.98
ENDCOMMENT
NEURON {
SUFFIX Golgi_CALC_ca2
USEION ca2 READ ica2, ca2o WRITE ca2i VALENCE 2
RANGE d, beta, ca2i0, ca2_pump_i
}
UNITS {
(mV) = (millivolt)
(mA) = (milliamp)
(um) = (micron)
(molar) = (1/liter)
(mM) = (millimolar)
F = (faraday) (coulomb)
}
PARAMETER {
ica2 (mA/cm2)
celsius (degC)
d = .2 (um)
ca2o (mM)
ca2i0 (mM)
beta = 1.3 (/ms)
}
ASSIGNED {
ca2_pump_i (mA)
}
STATE {
ca2i (mM)
}
INITIAL {
ca2i = ca2i0
}
BREAKPOINT {
SOLVE conc METHOD derivimplicit
}
DERIVATIVE conc {
: outward ionic current with valence 2+
ca2_pump_i = 2*beta*(ca2i-ca2i0)
: total outward Ca2 current
ca2i' = -ica2/(2*F*d)*(1e4) - beta*(ca2i-ca2i0)
}