This code generates the key results figures shown in Kerr CC, Neymotin SA, Chadderdon GL, Fietkiewicz CT, Francis JT, Lytton WW (2012). Electrostimulation as a prosthesis for repair of information flow in a computer model of neocortex. IEEE Transactions on Neural Systems & Rehabilitation Engineering 20(2):153–60. This document provides brief installation and usage instructions. INSTALLATION Note: the code has been designed to work on Linux machines. It may work on Macs and will definitely not work on Windows. If this is a problem, please contact Cliff Kerr (cliffk@neurosim.downstate.edu) for assistance. Dependencies: 1. NEURON 2. Python 3. Pylab, SciPy, NumPy, and Matplotlib. Instructions: 1. Unzip all files (which it looks like you've already done). 2. Type "nrnivmodl *.mod" in the directory. This should create a directory called either i686 or x86_64, depending on your computer's architecture, and put a file called "special" in that directory. USAGE 1. Type "runsim". Two graphs should appear, corresponding to the two types of results figures in the paper. OPTIONS * To adjust cortical vs. thalamic damage, simulation time, and model size, please adjust the hopefully-clearly-labeled parameters in runsim. CHANGELOG 20121210 Unused packages were removed from Python scripts. 20220517 Updated MOD files to contain valid C++ and be compatible with the upcoming versions 8.2 and 9.0 of NEURON. Updated to use post ~2011 signature of mcell_ran4_init function and fix hashseed2 argument. 20230420 Updated MOD files for compatibility with data structures in the upcoming version 9.0 of NEURON.