: Leak Current Model, Bob Calin-Jageman 9/20/2002
: This model implements a simple leak function described by
: Getting, 1989 and utilized by Lieb and Frost, 1998.
:
:
: Created by Bob Calin-Jageman
:
: Created 9/20/2002
: Modified 9/20/2002
:
: Mathcheck - Complete 9/31/2002
: Unitscheck - questions about resistance units
:
: Explanation
: Leak current calculated as difference between current and resting membrane
: potentials divided by resistance
:
: Resistance should be in megaOhms
: resting potential should be in millivolts
: output current will be in milliamps
:
: References
: Getting, P.A. (1989) "Reconstruction of small neural networks" in
: Methods in Neuronal Modeling: From Synapses to Networks (1st ed), Kock & Segev
: eds, MIT Press.
: Lieb JR & Frost WN (1997) "Realistic Simulation of the Aplysia Siphon
: Withdrawal Reflex Circuit: Roles of Circuit Elements in Producing Motor Output"
: p. 1249 */
:
NEURON {
POINT_PROCESS leak
NONSPECIFIC_CURRENT i
RANGE r, vrest
}
UNITS {
(mV) = (millivolt)
(nA) = (nanoamp)
}
PARAMETER {
r = 15.7 (megaohm)
vrest = -45 (mV)
}
ASSIGNED {
i (nA)
v (mV)
}
BREAKPOINT {
i = (v - vrest)/r
}