NEURON {
SUFFIX Nav1_3
USEION na READ ena WRITE ina
RANGE gNav1_3bar, gNav1_3, ina, BBiD, hTau, gbar
}
UNITS {
(S) = (siemens)
(mV) = (millivolt)
(mA) = (milliamp)
}
PARAMETER {
gbar = 0.00001 (S/cm2)
BBiD = 122
}
ASSIGNED {
v (mV)
ena (mV)
ina (mA/cm2)
gNav1_3 (S/cm2)
mInf
mTau
mAlpha
mBeta
hInf
hTau
}
STATE {
m
h
}
BREAKPOINT {
SOLVE states METHOD cnexp
gNav1_3 = gbar*m*m*m*h
ina = gNav1_3*(v-ena)
}
DERIVATIVE states {
rates()
m' = (mInf-m)/mTau
h' = (hInf-h)/hTau
}
INITIAL{
rates()
m = mInf
h = hInf
}
PROCEDURE rates(){
UNITSOFF
if(v == -26){
v = v + 0.000001
}
mAlpha = (0.182 * ((v)- -26))/(1-(exp(-((v)- -26)/9)))
if(v == -26){
v = v + 0.000001
}
mBeta = (0.124 * (-(v) -26))/(1-(exp(-(-(v) -26)/9)))
mInf = mAlpha/(mAlpha + mBeta)
mTau = 1/(mAlpha + mBeta)
hInf = 1 /(1+exp((v-(-65.0))/8.1))
hTau = 0.40 + (0.265 * exp(-v/9.47))
UNITSON
}