// Granule cell model of Migliore and Shepherd // keep only primary dendrite // Translated by Aditya NCBS 2010. // fields are .. // name // parent // x,y,z // coords of endpoint. // dia // needed for memb props. All lengths are in microns. // ch name density // ch name density // ..... // Control lines start with '*'. Valid control options are // *relative - relative coords. // *absolute - absolute coords. // *asymmetric - use asymmetric compartments // *symmetric - use symmetric compartments // # name parent x y z d ch dens ch dens . . . *symmetric //Neuron has only symmetric compartments - however hsolve symmetrizes the Ra-s internally. // With the present implementation, it doesn't matter whether you write symmetric or asymmetric here. *relative *set_global EREST_ACT -0.065 // reduced two compartmental granule adapted from Migliore and Shepherd *cartesian *start_cell // Both Migliore and Shepherd 2008 and Egger et al 2003 say taum = 30ms, Rin=1GOhm. So set RM and CM for it. *set_global RA 0.8 // Ohm-m from 80 Ohm-cm *set_global CM 0.04 // F/m^2 //*set_global RM 0.75 // RM = 30e-3/CM = 0.75 Ohm-m^2 // Aditya: I reduced CM to 0.02 from 0.04. Thus time constant is now 15ms not 30ms. *set_global RM 0.75 // RM = 30e-3/CM = 0.75 Ohm-m^2 // soma is somagc of gc.hoc of Migliore and Shepherd 2008. soma none 8 0 0 8 Na_rat_ms 400 KDR_ms 60 KA_ms 40 // periphery is priden of gc.hoc of Migliore and Shepherd 2008. // Following Migliore and Shepherd 2008, I have only KA and not KDR in dendrites! This is supposed to cause spike latency periphery soma 150 0 0 0.5 Na_rat_ms 200 KA_ms 80