/* Created by Language version: 7.5.0 */
/* NOT VECTORIZED */
#define NRN_VECTORIZED 0
#include <stdio.h>
#include <stdlib.h>
#include <math.h>
#include "scoplib_ansi.h"
#undef PI
#define nil 0
#include "md1redef.h"
#include "section.h"
#include "nrniv_mf.h"
#include "md2redef.h"
 
#if METHOD3
extern int _method3;
#endif

#if !NRNGPU
#undef exp
#define exp hoc_Exp
extern double hoc_Exp(double);
#endif
 
#define nrn_init _nrn_init__ca
#define _nrn_initial _nrn_initial__ca
#define nrn_cur _nrn_cur__ca
#define _nrn_current _nrn_current__ca
#define nrn_jacob _nrn_jacob__ca
#define nrn_state _nrn_state__ca
#define _net_receive _net_receive__ca 
#define _f_trates _f_trates__ca 
#define rates rates__ca 
#define states states__ca 
#define trates trates__ca 
 
#define _threadargscomma_ /**/
#define _threadargsprotocomma_ /**/
#define _threadargs_ /**/
#define _threadargsproto_ /**/
 	/*SUPPRESS 761*/
	/*SUPPRESS 762*/
	/*SUPPRESS 763*/
	/*SUPPRESS 765*/
	 extern double *getarg();
 static double *_p; static Datum *_ppvar;
 
#define t nrn_threads->_t
#define dt nrn_threads->_dt
#define gbar _p[0]
#define gca _p[1]
#define minf _p[2]
#define hinf _p[3]
#define mtau _p[4]
#define htau _p[5]
#define m _p[6]
#define h _p[7]
#define ica _p[8]
#define eca _p[9]
#define Dm _p[10]
#define Dh _p[11]
#define _g _p[12]
#define _ion_eca	*_ppvar[0]._pval
#define _ion_ica	*_ppvar[1]._pval
#define _ion_dicadv	*_ppvar[2]._pval
 
#if MAC
#if !defined(v)
#define v _mlhv
#endif
#if !defined(h)
#define h _mlhh
#endif
#endif
 
#if defined(__cplusplus)
extern "C" {
#endif
 static int hoc_nrnpointerindex =  -1;
 /* external NEURON variables */
 extern double celsius;
 /* declaration of user functions */
 static void _hoc_efun(void);
 static void _hoc_rates(void);
 static void _hoc_trates(void);
 static int _mechtype;
extern void _nrn_cacheloop_reg(int, int);
extern void hoc_register_prop_size(int, int, int);
extern void hoc_register_limits(int, HocParmLimits*);
extern void hoc_register_units(int, HocParmUnits*);
extern void nrn_promote(Prop*, int, int);
extern Memb_func* memb_func;
 extern void _nrn_setdata_reg(int, void(*)(Prop*));
 static void _setdata(Prop* _prop) {
 _p = _prop->param; _ppvar = _prop->dparam;
 }
 static void _hoc_setdata() {
 Prop *_prop, *hoc_getdata_range(int);
 _prop = hoc_getdata_range(_mechtype);
   _setdata(_prop);
 hoc_retpushx(1.);
}
 /* connect user functions to hoc names */
 static VoidFunc hoc_intfunc[] = {
 "setdata_ca", _hoc_setdata,
 "efun_ca", _hoc_efun,
 "rates_ca", _hoc_rates,
 "trates_ca", _hoc_trates,
 0, 0
};
#define efun efun_ca
 extern double efun( double );
 /* declare global and static user variables */
#define cai cai_ca
 double cai = 0;
#define cao cao_ca
 double cao = 2.5;
#define q10 q10_ca
 double q10 = 2.3;
#define tadj tadj_ca
 double tadj = 0;
#define temp temp_ca
 double temp = 23;
#define usetable usetable_ca
 double usetable = 1;
#define vshift vshift_ca
 double vshift = 0;
#define vmax vmax_ca
 double vmax = 100;
#define vmin vmin_ca
 double vmin = -120;
 /* some parameters have upper and lower limits */
 static HocParmLimits _hoc_parm_limits[] = {
 "usetable_ca", 0, 1,
 0,0,0
};
 static HocParmUnits _hoc_parm_units[] = {
 "vshift_ca", "mV",
 "cao_ca", "mM",
 "cai_ca", "mM",
 "temp_ca", "degC",
 "vmin_ca", "mV",
 "vmax_ca", "mV",
 "gbar_ca", "pS/um2",
 "gca_ca", "pS/um2",
 "mtau_ca", "ms",
 "htau_ca", "ms",
 0,0
};
 static double delta_t = 1;
 static double h0 = 0;
 static double m0 = 0;
 static double v = 0;
 /* connect global user variables to hoc */
 static DoubScal hoc_scdoub[] = {
 "vshift_ca", &vshift_ca,
 "cao_ca", &cao_ca,
 "cai_ca", &cai_ca,
 "temp_ca", &temp_ca,
 "q10_ca", &q10_ca,
 "vmin_ca", &vmin_ca,
 "vmax_ca", &vmax_ca,
 "tadj_ca", &tadj_ca,
 "usetable_ca", &usetable_ca,
 0,0
};
 static DoubVec hoc_vdoub[] = {
 0,0,0
};
 static double _sav_indep;
 static void nrn_alloc(Prop*);
static void  nrn_init(_NrnThread*, _Memb_list*, int);
static void nrn_state(_NrnThread*, _Memb_list*, int);
 static void nrn_cur(_NrnThread*, _Memb_list*, int);
static void  nrn_jacob(_NrnThread*, _Memb_list*, int);
 
static int _ode_count(int);
static void _ode_map(int, double**, double**, double*, Datum*, double*, int);
static void _ode_spec(_NrnThread*, _Memb_list*, int);
static void _ode_matsol(_NrnThread*, _Memb_list*, int);
 
#define _cvode_ieq _ppvar[3]._i
 static void _ode_matsol_instance1(_threadargsproto_);
 /* connect range variables in _p that hoc is supposed to know about */
 static const char *_mechanism[] = {
 "7.5.0",
"ca",
 "gbar_ca",
 0,
 "gca_ca",
 "minf_ca",
 "hinf_ca",
 "mtau_ca",
 "htau_ca",
 0,
 "m_ca",
 "h_ca",
 0,
 0};
 static Symbol* _ca_sym;
 
extern Prop* need_memb(Symbol*);

static void nrn_alloc(Prop* _prop) {
	Prop *prop_ion;
	double *_p; Datum *_ppvar;
 	_p = nrn_prop_data_alloc(_mechtype, 13, _prop);
 	/*initialize range parameters*/
 	gbar = 0.1;
 	_prop->param = _p;
 	_prop->param_size = 13;
 	_ppvar = nrn_prop_datum_alloc(_mechtype, 4, _prop);
 	_prop->dparam = _ppvar;
 	/*connect ionic variables to this model*/
 prop_ion = need_memb(_ca_sym);
 nrn_promote(prop_ion, 0, 1);
 	_ppvar[0]._pval = &prop_ion->param[0]; /* eca */
 	_ppvar[1]._pval = &prop_ion->param[3]; /* ica */
 	_ppvar[2]._pval = &prop_ion->param[4]; /* _ion_dicadv */
 
}
 static void _initlists();
  /* some states have an absolute tolerance */
 static Symbol** _atollist;
 static HocStateTolerance _hoc_state_tol[] = {
 0,0
};
 static void _update_ion_pointer(Datum*);
 extern Symbol* hoc_lookup(const char*);
extern void _nrn_thread_reg(int, int, void(*)(Datum*));
extern void _nrn_thread_table_reg(int, void(*)(double*, Datum*, Datum*, _NrnThread*, int));
extern void hoc_register_tolerance(int, HocStateTolerance*, Symbol***);
extern void _cvode_abstol( Symbol**, double*, int);

 void _ca_reg() {
	int _vectorized = 0;
  _initlists();
 	ion_reg("ca", -10000.);
 	_ca_sym = hoc_lookup("ca_ion");
 	register_mech(_mechanism, nrn_alloc,nrn_cur, nrn_jacob, nrn_state, nrn_init, hoc_nrnpointerindex, 0);
 _mechtype = nrn_get_mechtype(_mechanism[1]);
     _nrn_setdata_reg(_mechtype, _setdata);
     _nrn_thread_reg(_mechtype, 2, _update_ion_pointer);
  hoc_register_prop_size(_mechtype, 13, 4);
  hoc_register_dparam_semantics(_mechtype, 0, "ca_ion");
  hoc_register_dparam_semantics(_mechtype, 1, "ca_ion");
  hoc_register_dparam_semantics(_mechtype, 2, "ca_ion");
  hoc_register_dparam_semantics(_mechtype, 3, "cvodeieq");
 	hoc_register_cvode(_mechtype, _ode_count, _ode_map, _ode_spec, _ode_matsol);
 	hoc_register_tolerance(_mechtype, _hoc_state_tol, &_atollist);
 	hoc_register_var(hoc_scdoub, hoc_vdoub, hoc_intfunc);
 	ivoc_help("help ?1 ca /Users/Penny/Dropbox/ModelDB/mod/x86_64/ca.mod\n");
 hoc_register_limits(_mechtype, _hoc_parm_limits);
 hoc_register_units(_mechtype, _hoc_parm_units);
 }
 static double FARADAY = 96485.3;
 static double R = 8.3145;
 static double PI = 3.14159;
 static double _zmexp , _zhexp ;
 static double *_t_minf;
 static double *_t_hinf;
 static double *_t_mtau;
 static double *_t_htau;
static int _reset;
static char *modelname = "";

static int error;
static int _ninits = 0;
static int _match_recurse=1;
static void _modl_cleanup(){ _match_recurse=1;}
static int _f_trates(double);
static int rates(double);
static int trates(double);
 
static int _ode_spec1(_threadargsproto_);
/*static int _ode_matsol1(_threadargsproto_);*/
 static void _n_trates(double);
 static int _slist1[2], _dlist1[2];
 static int states(_threadargsproto_);
 
/*CVODE*/
 static int _ode_spec1 () {_reset=0;
 {
   trates ( _threadargscomma_ v + vshift ) ;
   Dm = ( minf - m ) / mtau ;
   Dh = ( hinf - h ) / htau ;
   }
 return _reset;
}
 static int _ode_matsol1 () {
 trates ( _threadargscomma_ v + vshift ) ;
 Dm = Dm  / (1. - dt*( ( ( ( - 1.0 ) ) ) / mtau )) ;
 Dh = Dh  / (1. - dt*( ( ( ( - 1.0 ) ) ) / htau )) ;
  return 0;
}
 /*END CVODE*/
 static int states () {_reset=0;
 {
   trates ( _threadargscomma_ v + vshift ) ;
    m = m + (1. - exp(dt*(( ( ( - 1.0 ) ) ) / mtau)))*(- ( ( ( minf ) ) / mtau ) / ( ( ( ( - 1.0 ) ) ) / mtau ) - m) ;
    h = h + (1. - exp(dt*(( ( ( - 1.0 ) ) ) / htau)))*(- ( ( ( hinf ) ) / htau ) / ( ( ( ( - 1.0 ) ) ) / htau ) - h) ;
   }
  return 0;
}
 static double _mfac_trates, _tmin_trates;
 static void _check_trates();
 static void _check_trates() {
  static int _maktable=1; int _i, _j, _ix = 0;
  double _xi, _tmax;
  static double _sav_celsius;
  static double _sav_temp;
  if (!usetable) {return;}
  if (_sav_celsius != celsius) { _maktable = 1;}
  if (_sav_temp != temp) { _maktable = 1;}
  if (_maktable) { double _x, _dx; _maktable=0;
   _tmin_trates =  vmin ;
   _tmax =  vmax ;
   _dx = (_tmax - _tmin_trates)/199.; _mfac_trates = 1./_dx;
   for (_i=0, _x=_tmin_trates; _i < 200; _x += _dx, _i++) {
    _f_trates(_x);
    _t_minf[_i] = minf;
    _t_hinf[_i] = hinf;
    _t_mtau[_i] = mtau;
    _t_htau[_i] = htau;
   }
   _sav_celsius = celsius;
   _sav_temp = temp;
  }
 }

 static int trates(double _lv){ _check_trates();
 _n_trates(_lv);
 return 0;
 }

 static void _n_trates(double _lv){ int _i, _j;
 double _xi, _theta;
 if (!usetable) {
 _f_trates(_lv); return; 
}
 _xi = _mfac_trates * (_lv - _tmin_trates);
 if (isnan(_xi)) {
  minf = _xi;
  hinf = _xi;
  mtau = _xi;
  htau = _xi;
  return;
 }
 if (_xi <= 0.) {
 minf = _t_minf[0];
 hinf = _t_hinf[0];
 mtau = _t_mtau[0];
 htau = _t_htau[0];
 return; }
 if (_xi >= 199.) {
 minf = _t_minf[199];
 hinf = _t_hinf[199];
 mtau = _t_mtau[199];
 htau = _t_htau[199];
 return; }
 _i = (int) _xi;
 _theta = _xi - (double)_i;
 minf = _t_minf[_i] + _theta*(_t_minf[_i+1] - _t_minf[_i]);
 hinf = _t_hinf[_i] + _theta*(_t_hinf[_i+1] - _t_hinf[_i]);
 mtau = _t_mtau[_i] + _theta*(_t_mtau[_i+1] - _t_mtau[_i]);
 htau = _t_htau[_i] + _theta*(_t_htau[_i+1] - _t_htau[_i]);
 }

 
static int  _f_trates (  double _lv ) {
   rates ( _threadargscomma_ _lv ) ;
    return 0; }
 
static void _hoc_trates(void) {
  double _r;
    _r = 1.;
 trates (  *getarg(1) );
 hoc_retpushx(_r);
}
 
static int  rates (  double _lvm ) {
   double _la , _lb ;
 tadj = pow( q10 , ( ( celsius - temp ) / 10.0 ) ) ;
   _la = 0.055 * ( - 27.0 - _lvm ) / ( exp ( ( - 27.0 - _lvm ) / 3.8 ) - 1.0 ) ;
   _lb = 0.94 * exp ( ( - 75.0 - _lvm ) / 17.0 ) ;
   mtau = 1.0 / tadj / ( _la + _lb ) ;
   minf = _la / ( _la + _lb ) ;
   _la = 0.000457 * exp ( ( - 13.0 - _lvm ) / 50.0 ) ;
   _lb = 0.0065 / ( exp ( ( - _lvm - 15.0 ) / 28.0 ) + 1.0 ) ;
   htau = 1.0 / tadj / ( _la + _lb ) ;
   hinf = _la / ( _la + _lb ) ;
    return 0; }
 
static void _hoc_rates(void) {
  double _r;
   _r = 1.;
 rates (  *getarg(1) );
 hoc_retpushx(_r);
}
 
double efun (  double _lz ) {
   double _lefun;
 if ( fabs ( _lz ) < 1e-4 ) {
     _lefun = 1.0 - _lz / 2.0 ;
     }
   else {
     _lefun = _lz / ( exp ( _lz ) - 1.0 ) ;
     }
   
return _lefun;
 }
 
static void _hoc_efun(void) {
  double _r;
   _r =  efun (  *getarg(1) );
 hoc_retpushx(_r);
}
 
static int _ode_count(int _type){ return 2;}
 
static void _ode_spec(_NrnThread* _nt, _Memb_list* _ml, int _type) {
   Datum* _thread;
   Node* _nd; double _v; int _iml, _cntml;
  _cntml = _ml->_nodecount;
  _thread = _ml->_thread;
  for (_iml = 0; _iml < _cntml; ++_iml) {
    _p = _ml->_data[_iml]; _ppvar = _ml->_pdata[_iml];
    _nd = _ml->_nodelist[_iml];
    v = NODEV(_nd);
  eca = _ion_eca;
     _ode_spec1 ();
  }}
 
static void _ode_map(int _ieq, double** _pv, double** _pvdot, double* _pp, Datum* _ppd, double* _atol, int _type) { 
 	int _i; _p = _pp; _ppvar = _ppd;
	_cvode_ieq = _ieq;
	for (_i=0; _i < 2; ++_i) {
		_pv[_i] = _pp + _slist1[_i];  _pvdot[_i] = _pp + _dlist1[_i];
		_cvode_abstol(_atollist, _atol, _i);
	}
 }
 
static void _ode_matsol_instance1(_threadargsproto_) {
 _ode_matsol1 ();
 }
 
static void _ode_matsol(_NrnThread* _nt, _Memb_list* _ml, int _type) {
   Datum* _thread;
   Node* _nd; double _v; int _iml, _cntml;
  _cntml = _ml->_nodecount;
  _thread = _ml->_thread;
  for (_iml = 0; _iml < _cntml; ++_iml) {
    _p = _ml->_data[_iml]; _ppvar = _ml->_pdata[_iml];
    _nd = _ml->_nodelist[_iml];
    v = NODEV(_nd);
  eca = _ion_eca;
 _ode_matsol_instance1(_threadargs_);
 }}
 extern void nrn_update_ion_pointer(Symbol*, Datum*, int, int);
 static void _update_ion_pointer(Datum* _ppvar) {
   nrn_update_ion_pointer(_ca_sym, _ppvar, 0, 0);
   nrn_update_ion_pointer(_ca_sym, _ppvar, 1, 3);
   nrn_update_ion_pointer(_ca_sym, _ppvar, 2, 4);
 }

static void initmodel() {
  int _i; double _save;_ninits++;
 _save = t;
 t = 0.0;
{
  h = h0;
  m = m0;
 {
   trates ( _threadargscomma_ v + vshift ) ;
   m = minf ;
   h = hinf ;
   }
  _sav_indep = t; t = _save;

}
}

static void nrn_init(_NrnThread* _nt, _Memb_list* _ml, int _type){
Node *_nd; double _v; int* _ni; int _iml, _cntml;
#if CACHEVEC
    _ni = _ml->_nodeindices;
#endif
_cntml = _ml->_nodecount;
for (_iml = 0; _iml < _cntml; ++_iml) {
 _p = _ml->_data[_iml]; _ppvar = _ml->_pdata[_iml];
#if CACHEVEC
  if (use_cachevec) {
    _v = VEC_V(_ni[_iml]);
  }else
#endif
  {
    _nd = _ml->_nodelist[_iml];
    _v = NODEV(_nd);
  }
 v = _v;
  eca = _ion_eca;
 initmodel();
 }}

static double _nrn_current(double _v){double _current=0.;v=_v;{ {
   gca = tadj * gbar * m * m * h ;
   ica = ( 1e-4 ) * gca * ( v - eca ) ;
   }
 _current += ica;

} return _current;
}

static void nrn_cur(_NrnThread* _nt, _Memb_list* _ml, int _type){
Node *_nd; int* _ni; double _rhs, _v; int _iml, _cntml;
#if CACHEVEC
    _ni = _ml->_nodeindices;
#endif
_cntml = _ml->_nodecount;
for (_iml = 0; _iml < _cntml; ++_iml) {
 _p = _ml->_data[_iml]; _ppvar = _ml->_pdata[_iml];
#if CACHEVEC
  if (use_cachevec) {
    _v = VEC_V(_ni[_iml]);
  }else
#endif
  {
    _nd = _ml->_nodelist[_iml];
    _v = NODEV(_nd);
  }
  eca = _ion_eca;
 _g = _nrn_current(_v + .001);
 	{ double _dica;
  _dica = ica;
 _rhs = _nrn_current(_v);
  _ion_dicadv += (_dica - ica)/.001 ;
 	}
 _g = (_g - _rhs)/.001;
  _ion_ica += ica ;
#if CACHEVEC
  if (use_cachevec) {
	VEC_RHS(_ni[_iml]) -= _rhs;
  }else
#endif
  {
	NODERHS(_nd) -= _rhs;
  }
 
}}

static void nrn_jacob(_NrnThread* _nt, _Memb_list* _ml, int _type){
Node *_nd; int* _ni; int _iml, _cntml;
#if CACHEVEC
    _ni = _ml->_nodeindices;
#endif
_cntml = _ml->_nodecount;
for (_iml = 0; _iml < _cntml; ++_iml) {
 _p = _ml->_data[_iml];
#if CACHEVEC
  if (use_cachevec) {
	VEC_D(_ni[_iml]) += _g;
  }else
#endif
  {
     _nd = _ml->_nodelist[_iml];
	NODED(_nd) += _g;
  }
 
}}

static void nrn_state(_NrnThread* _nt, _Memb_list* _ml, int _type){
Node *_nd; double _v = 0.0; int* _ni; int _iml, _cntml;
#if CACHEVEC
    _ni = _ml->_nodeindices;
#endif
_cntml = _ml->_nodecount;
for (_iml = 0; _iml < _cntml; ++_iml) {
 _p = _ml->_data[_iml]; _ppvar = _ml->_pdata[_iml];
 _nd = _ml->_nodelist[_iml];
#if CACHEVEC
  if (use_cachevec) {
    _v = VEC_V(_ni[_iml]);
  }else
#endif
  {
    _nd = _ml->_nodelist[_iml];
    _v = NODEV(_nd);
  }
 v=_v;
{
  eca = _ion_eca;
 { error =  states();
 if(error){fprintf(stderr,"at line 74 in file ca.mod:\n        SOLVE states METHOD cnexp\n"); nrn_complain(_p); abort_run(error);}
 } }}

}

static void terminal(){}

static void _initlists() {
 int _i; static int _first = 1;
  if (!_first) return;
 _slist1[0] = &(m) - _p;  _dlist1[0] = &(Dm) - _p;
 _slist1[1] = &(h) - _p;  _dlist1[1] = &(Dh) - _p;
   _t_minf = makevector(200*sizeof(double));
   _t_hinf = makevector(200*sizeof(double));
   _t_mtau = makevector(200*sizeof(double));
   _t_htau = makevector(200*sizeof(double));
_first = 0;
}