<?xml version="1.0" encoding="ISO-8859-1"?> <neuroml xmlns="http://www.neuroml.org/schema/neuroml2" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.neuroml.org/schema/neuroml2 https://raw.github.com/NeuroML/NeuroML2/development/Schemas/NeuroML2/NeuroML_v2beta4.xsd" id="SKv3_1"> <notes>NeuroML file containing a single Channel description</notes> <ionChannel id="SKv3_1" conductance="10pS" type="ionChannelHH" species="k"> <notes>Fast, non inactivating K+ current Comment from original mod file: :Reference : : Characterization of a Shaw-related potassium channel family in rat brain, The EMBO Journal, vol.11, no.7,2473-2486 (1992)</notes> <annotation> <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"> <rdf:Description rdf:about="SKv3_1"> <bqmodel:isDescribedBy xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> <rdf:Bag> <rdf:li>Models of Neocortical Layer 5b Pyramidal Cells Capturing a Wide Range of Dendritic and Perisomatic Active Properties, Etay Hay, Sean Hill, Felix Schürmann, Henry Markram and Idan Segev, PLoS Comp Biol 2011</rdf:li> <rdf:li rdf:resource="http://www.ncbi.nlm.nih.gov/pubmed/21829333"/> </rdf:Bag> </bqmodel:isDescribedBy> <bqbiol:isVersionOf xmlns:bqbiol="http://biomodels.net/biology-qualifiers/"> <rdf:Bag> <rdf:li>K channels</rdf:li> <rdf:li rdf:resource="http://senselab.med.yale.edu/neurondb/channelGene2.aspx#table3"/> </rdf:Bag> </bqbiol:isVersionOf> </rdf:Description> </rdf:RDF> </annotation> <gate id="m" type="gateHHtauInf" instances="1"> <timeCourse type="SKv3_1_m_tau_tau"/> <steadyState type="HHSigmoidVariable" rate="1" scale="9.7mV" midpoint="18.7mV"/> </gate> </ionChannel> <ComponentType name="SKv3_1_m_tau_tau" extends="baseVoltageDepTime"> <Constant name="TIME_SCALE" dimension="time" value="1 ms"/> <Constant name="VOLT_SCALE" dimension="voltage" value="1 mV"/> <Dynamics> <DerivedVariable name="V" dimension="none" value="v / VOLT_SCALE"/> <DerivedVariable name="t" exposure="t" dimension="time" value="(4/(1 + exp( (V+46.56) / (-44.140) ))) * TIME_SCALE"/> </Dynamics> </ComponentType> </neuroml>