:Reference : : Adams et al. 1982 - M-currents and other potassium currents in bullfrog sympathetic neurones
:Comment: corrected rates using q10 = 2.3, target temperature 34, orginal 21
NEURON {
SUFFIX Im
USEION k READ ek WRITE ik
RANGE gImbar, gIm, ik, offma, sloma, tauma, offmb, slomb, taumb
}
UNITS {
(S) = (siemens)
(mV) = (millivolt)
(mA) = (milliamp)
}
PARAMETER {
gImbar = 0.00001 (S/cm2)
offma = -35 (mV)
sloma = 10 (mV)
tauma = 303.0303 (ms)
offmb = -35 (mV)
slomb = 10 (mV)
taumb = 303.0303 (ms)
}
ASSIGNED {
v (mV)
ek (mV)
ik (mA/cm2)
gIm (S/cm2)
mInf
mTau
mAlpha
mBeta
}
STATE {
m
}
BREAKPOINT {
SOLVE states METHOD cnexp
gIm = gImbar*m
ik = gIm*(v-ek)
}
DERIVATIVE states {
rates()
m' = (mInf-m)/mTau
}
INITIAL{
rates()
m = mInf
}
PROCEDURE rates(){
LOCAL qt
qt = 2.3^((34-21)/10)
UNITSOFF
mAlpha = exp(-(offma-v)/sloma)/tauma
mBeta = exp((offmb-v)/slomb)/taumb
mInf = mAlpha/(mAlpha + mBeta)
mTau = (1/(mAlpha + mBeta))/qt
UNITSON
}