Two programs * sd-wild-type.ode * sd-mutation.ode See: M. A. Dahlem, J. Schumacher, and N. Huebel (2014) Linking a genetic defect in migraine to spreading depression in a computational model, PeerJ, 2:e379, http://dx.doi.org/10.7717/peerj.379 Purpose: Model spreading depression with an extended Hodgkin-Huxley framework that includes time-dependend ion concentrations and to establish a connection between a migraine genotype, namely the familial hemiplegic migraine type 3 (FHM3), and cellular phenotype of this disease. Code for xppaut. Email: markus.dahlem@gmail.com Web: https://sites.google.com/site/markusadahlem/