% # iA_PYso_JB12: % % Fast A-type potassium current, for generic pyramidal soma compartments used % in the DynaSim implementation of (Benita et al., 2012). The original paper % cites this mechanism from (Golomb and Amitai, 1997). % % - References: % - Benita, J. M., Guillamon, A., Deco, G., & Sanchez-Vives, M. V. (2012). % Synaptic depression and slow oscillatory activity in a biophysical % network model of the cerebral cortex. Frontiers in Computational % Neuroscience, 6. https://doi.org/10.3389/fncom.2012.00064 % - Golomb, D., & Amitai, Y. (1997). Propagating neuronal discharges in % neocortical slices: computational and experimental study. Journal of % Neurophysiology, 78(3), 1199–1211. % https://doi.org/10.1152/jn.1997.78.3.1199 % % - Tags: potassium, current, intrinsic, pyramidal, soma %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%% % Parameters gA = 1 % mS/cm^2 EA = -100 % mV, same as potassium reversal potential tauH = 15 % ms phi = 1 % temperature factor hAIC = 0.1 hANoiseIC = 0.1 % Functions Minf(X) = 1./(1 + exp(-(X+50)./20)) Hinf(X) = 1./(1 + exp((X+80)./6)) IA_PYso_JB12(X,hA) = -gA.*Minf(X).^3.*hA.*(X-EA) monitor IA_PYso_JB12 % ODEs and ICs hA' = phi.*(Hinf(X) - hA)./tauH hA(0)=hAIC+hANoiseIC.*rand(1, Npop) % Interface @current += IA_PYso_JB12(X,hA)