% # iHVA_PYdr_JB12: % % High-threshold Calcium current, Hodgkin-Huxley-style, for generic pyramidal % dendrite compartments used in the DynaSim implementation of (Benita et al., % 2012). Note that this is called "iCa" in the original paper. % % - References: % - Benita, J. M., Guillamon, A., Deco, G., & Sanchez-Vives, M. V. (2012). % Synaptic depression and slow oscillatory activity in a biophysical % network model of the cerebral cortex. Frontiers in Computational % Neuroscience, 6. https://doi.org/10.3389/fncom.2012.00064 % % - Exposes: @IHVA_PYdr_JB12 calcium current as required by "CaBuffer_PYdr_JB12" % % - Tags: calcium, current, intrinsic, pyramidal, dendrite %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%% % Parameters gHVA = 0.43 % mS/cm^2 EHVA = 120 % mV % Functions Minf(X) = 1./(1 + exp(-(X+20)./9)) % Note: For why the current term was not made negative, see below. % AES % IHVA_PYdr_JB12(X) = gHVA.*Minf(X).^2.*(X-EHVA) IHVA_PYdr_JB12(X) = -gHVA.*Minf(X).^2.*(X-EHVA) monitor IHVA_PYdr_JB12 % Interface % Note: Usually in DynaSim, the current is made negative % before being assigned to a linker, but in this case, the % below is less confusing since exposing IHVA_PYdr_JB12 for the % CaBuffer_PYdr_JB12 mechanism requires a not-made-negative % version of IHVA_PYdr_JB12. % AES % @current += -IHVA_PYdr_JB12(X) @current += IHVA_PYdr_JB12(X) @IHVA_PYdr_JB12 += IHVA_PYdr_JB12(X)