% # iKS_PYso_JB12: % % Non-inactivating potassium current, for generic pyramidal soma compartments % used in the DynaSim implementation of (Benita et al., 2012). The original % paper cites this mechanism from (Wang, 1999a). % % - References: % - Benita, J. M., Guillamon, A., Deco, G., & Sanchez-Vives, M. V. (2012). % Synaptic depression and slow oscillatory activity in a biophysical % network model of the cerebral cortex. Frontiers in Computational % Neuroscience, 6. https://doi.org/10.3389/fncom.2012.00064 % - Wang, X. J. (1999). Fast burst firing and short-term synaptic % plasticity: a model of neocortical chattering neurons. Neuroscience, % 89(2), 347–362. Retrieved from % https://www.ncbi.nlm.nih.gov/pubmed/10077318 % % - Tags: potassium, current, intrinsic, pyramidal, soma %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%% % Parameters gKS = 0.576 % mS/cm^2 EKS = -100 % mV, same as potassium reversal potential phi = 1 % temperature factor mKSIC = 0.005 mKSNoiseIC = 0.001 % Functions Minf(X) = 1./(1 + exp(-(X+34)./6.5)) tauM(X) = 8./(exp(-(X+55)./30) + exp((X+55)./30)) IKS_PYso_JB12(X,mKS) = -gKS.*mKS.^3.*(X-EKS) monitor IKS_PYso_JB12 % ODEs and ICs mKS' = phi.*(Minf(X) - mKS)./tauM(X) mKS(0)=mKSIC+mKSNoiseIC.*rand(1, Npop) % Interface @current += IKS_PYso_JB12(X,mKS)