% # iNa_IN_JB12: % % Fast sodium current for generic interneurons used in the % DynaSim implementation of (Benita et al., 2012). % % - References: % - Benita, J. M., Guillamon, A., Deco, G., & Sanchez-Vives, M. V. (2012). % Synaptic depression and slow oscillatory activity in a biophysical % network model of the cerebral cortex. Frontiers in Computational % Neuroscience, 6. https://doi.org/10.3389/fncom.2012.00064 % % - Tags: sodium, current, intrinsic, interneuron %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%% % Parameters gNa = 35 % mS/cm^2 ENa = 55 % mV hNaIC = 0.7 hNaNoiseIC = 0.1 % Functions alphaM(X) = 0.5.*(X+35)./(1-exp(-(X+35)./10)) betaM(X) = 20.*exp(-(X+60)./18) alphaH(X) = 0.35.*exp(-(X+58)./20) betaH(X) = 5./(1+exp(-(X+28)./10)) Minf(X) = alphaM(X)./(alphaM(X) + betaM(X)) INa_IN_JB12(X,hNa) = -gNa.*Minf(X).^3.*hNa.*(X-ENa) monitor INa_IN_JB12 monitor Minf % ODEs and ICs hNa' = (alphaH(X).*(1-hNa)) - (betaH(X).*hNa) hNa(0)=hNaIC+hNaNoiseIC.*rand(1, Npop) % Interface @current += INa_IN_JB12(X,hNa)