% # iNa_TC_AS17: % % Fast sodium current for generic thalamocortical cells used in (Soplata et % al., 2017). % % - References: % - Soplata AE, McCarthy MM, Sherfey J, Lee S, Purdon PL, Brown EN, et al. % Thalamocortical control of propofol phase-amplitude coupling. PLoS Comput % Biol. 2017;13: e1005879. doi:10.1371/journal.pcbi.1005879 % % - Tags: sodium, current, intrinsic, thalamus, thalamocortical %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%% % Parameters gNa = 90 % mS/cm^2 ENa = 50 % mV vShift = -40 % mV mNaIC = 0.00007 mNaNoiseIC = 0.00001 hNaIC = 0.8 hNaNoiseIC = 0.1 % Functions alphaM(X) = 0.32.*(13 - (X-vShift))./(exp((13 - (X-vShift))./4) - 1) betaM(X) = 0.28.*((X-vShift) - 40)./(exp(((X-vShift) - 40)./5) - 1) alphaH(X) = 0.128.*exp((17 - (X-vShift))./18) betaH(X) = 4./(exp((40 - (X-vShift))./5) + 1) iNa_TC_AS17(X,mNa,hNa) = -gNa.*mNa.^3.*hNa.*(X-ENa) monitor iNa_TC_AS17 % ODEs and ICs mNa' = alphaM(X).*(1-mNa) - betaM(X).*mNa; mNa(0)=mNaIC+mNaNoiseIC.*rand(1,Npop) hNa' = alphaH(X).*(1-hNa) - betaH(X).*hNa; hNa(0)=hNaIC+hNaNoiseIC.*rand(1,Npop) % Linker @current += iNa_TC_AS17(X,mNa,hNa)