proc reset_testcell() {
biophysics()
typeB_slow()
ca_init = 1e-4
cainf_cad = 1e-4
v_init = -52
ek = -80
}
proc deep_singleAHP() {
reset_testcell()
gnabar_fn = 0.018
gbar_ka = 0.0071
gbar_cahi = 0.001
gbar_nap = 1e-9
Kp_cad = 1
Rca_cad = 5
}
proc single_spike() {
reset_testcell()
Kp_cad = 0.025
Rca_cad = 0.00625
}
proc slower_FR() {
reset_testcell()
Kp_cad = 0.0325
Rca_cad = 0.008125
}
proc higher_FR() {
reset_testcell()
Kp_cad = 0.1
Rca_cad = 0.025
}
proc shallow_AHP() {
reset_testcell()
gnabar_fn = 0.02
}
proc no_spikes() {
reset_testcell()
gbar_kca *= 2
}
proc burst_example() {
reset_testcell()
gnabar_fn = 0.01
gkbar_fn = 0.004
//kca, cahi different from default
gbar_kca = 0.00025
gbar_cahi = 0.001
gbar_ka = 1e-9
gbar_nap = 5e-5
Kp_cad = 0.05
Rca_cad = 0.0125
}
/*** Av-Ron's Minimal Cell Model ***/
proc setMCM() {
gbar_nap = 0
gbar_cahi = 0
gbar_kca = 0
gbar_ka = 1e-9
v_init = -56
gkbar_fn = 0.010
vhm_fn = -31
am_fn = 0.065
vhn_fn = -46
an_fn = 0.055
lamb_fn = 0.08
gnabar_fn = 0.120
g_pas = 0.0003
ena = 55
ek = -72
e_pas = -50
}
proc setburst() {
setMCM()
simp_cahi = 1
gkbar_fn = 0.005
gbar_kca = 0.0005
Kd_kca = 0.0005
gbar_cahi = 0.0002
ek = -72
eca = 124
vrest_cahi = 124
Kp_cad = 0.0005
Rca_cad = 0.003
cainf_cad = 1e-5
vhx_cahi = -40
ax_cahi = 0.2
xtau_cahi = 50
simp_cahi=0
}
proc adapting() {
reset_testcell()
Kp_cad = 0.04
Rca_cad = 0.0005
gbar_kca = .0003
}
proc burst_cond() {
reset_testcell()
gbar_nap = 0
gbar_ka = 1e-9
gnabar_fn = 0.1
gkbar_fn = 0.005
gbar_kca = 0.0005
gbar_cahi = 0.0002
Kp_cad = 0.05
Rca_cad = 0.03
cainf_cad = 1e-5
}