TITLE K-D
: K-D current for prefrontal cortical neuron ------Yuguo Yu 2007
NEURON {
SUFFIX kd
USEION k READ ek WRITE ik
RANGE gk, gbar, i
GLOBAL minf, mtau, hinf, htau
}
PARAMETER {
gbar = 0.1 (S/cm2)
celsius
ek = -100 (mV)
v (mV)
vhalfm=-43 (mV)
km=8
vhalfh=-67 (mV)
kh=7.3
q10=2.3
}
UNITS {
(mA) = (milliamp)
(mV) = (millivolt)
(pS) = (picosiemens)
(um) = (micron)
}
ASSIGNED {
i (mA/cm2)
ik (mA/cm2)
minf
mtau (ms)
hinf
htau (ms)
}
STATE { m h}
BREAKPOINT {
SOLVE states METHOD cnexp
i = gbar*m*h*(v-ek)
ik=i
}
INITIAL {
trates(v)
m=minf
h=hinf
}
DERIVATIVE states {
trates(v)
m' = (minf-m)/mtau
h' = (hinf-h)/htau
}
PROCEDURE trates(v) {
LOCAL qt
qt=q10^((celsius-22)/10)
minf=1-1/(1+exp((v-vhalfm)/km))
hinf=1/(1+exp((v-vhalfh)/kh))
mtau = 0.6
htau = 1500
}