TITLE sEPSP COMMENT ----------------------------------------------------------------------------- sEPSP current model for summation analysis ================================================== IMPLEMENTATION This mechanism is implemented as a nonspecific current defined as a point process, mimicking a current-clamp stimulation protocol, injecting simulated EPSP I(t). I = 0 for t < onset and I(t) = A*(1 - exp(-1*(t-onset)/tau_r)) * (exp(1 - (t-onset) / tau_f)) for t > onset > t+offset I = 0 for t > offset PARAMETERS This mechanism takes the following parameters: A = 1.0 (nA) : initial current offset taur = 0.3 (ms) : time constant of rise tauf = 3.0 (ms) : time constant of fall onset = 0.0 (ms) : start time of current offset = onset+20 (ms) ----------------------------------------------------------------------------- ENDCOMMENT NEURON { POINT_PROCESS sEPSP RANGE A, onset, i NONSPECIFIC_CURRENT i } UNITS { (nA) = (nanoamp) } PARAMETER { A = 0.0 (nA) : initial current offset. taur = 0.3 (ms) : time constant of rise. tauf = 3.0 (ms) : time constant of fall. onset = 0.0 (ms) : start time of current } ASSIGNED { i (nA) : injected current } BREAKPOINT { if ((t < onset) || (t > onset+20)) { i = 0 } else { i = -A*(1 - exp(-1*(t-onset)/taur)) * (exp(1 - (t-onset) / tauf)) } }