TITLE Cerebellum Granule Cell Model leakage COMMENT Reference: Theta-Frequency Bursting and Resonance in Cerebellar Granule Cells:Experimental Evidence and Modeling of a Slow K+-Dependent Mechanism Egidio D'Angelo,Thierry Nieus,Arianna Maffei,Simona Armano,Paola Rossi,Vanni Taglietti, Andrea Fontana and Giovanni Naldi SAT: its a distributed mechanism with out any dynamic behaviour. Its just modified from Granular cell's leakage channel. ENDCOMMENT NEURON { SUFFIX Ubc_TRP NONSPECIFIC_CURRENT itrp :USEION cAMP READ cAMPi VALENCE 0 USEION ca READ cai USEION con_2c READ con_2ci VALENCE 1 RANGE etrp, gtrp, i, itrp, fcAMP, TonicTRP } UNITS { (mA) = (milliamp) (mV) = (millivolt) } PARAMETER { v (mV) gtrp = 4.18e-6 (mho/cm2) celsius = 30 (degC) etrp = 0 (mV) fcAMP = 1 theta = 0 (1) TonicTRP = 0.05 } ASSIGNED { cAMPi (mM) cai (mM) itrp (mA/cm2) i (mA/cm2) con_2ci (mM) } BREAKPOINT { :printf("cai %g\n",cai) if(con_2ci > 0.0075){ itrp = (gtrp*(v - etrp) * (1 + (3*con_2ci))) }else { itrp = 0 :gtrp*(v - etrp) *0.01 } i = itrp : printf("cAMPi: %g \t itrp: %g",cAMPi) }