This is the readme for the model associated with the paper:

Antunes G, Sebastiao AM, Simoes de Souza FM (2014) Mechanisms of regulation of olfactory transduction and adaptation in the olfactory cilium. PLoS One 9:e105531

This model was contributed by Fabio Marques Simoes de Souza.

COPASI, free software, is required for this model and is available, along with documentation, from http://www.copasi.org/

Example Usage:
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Start COPASIUI and open model_treatment.cps. Select Time Course and click on Run. You should see a graph of Ca2+ generated:

The figures in the paper are the mean results from hundreds of single runs. The screen shot reproduces a single run of the model. Supplementary figure S3, first column (A to E) shows the example of 5 single runs. The first column of Fig. S3 panel F shows the mean result of hundred simulations. We used the Condor Copasi platform to do it automatically: https://www.nimml.org/tools/copasi-suite/condor-copasi (There is a similar relationship between model_control.cps and supplementary figure 2).