This is the readme for the model associated with the paper:

Proddutur A, Yu J, Elgammal FS, Santhakumar V (2013) Seizure-induced
alterations in fast-spiking basket cell GABA currents modulate
frequency and coherence of gamma oscillation in network
simulations. Chaos 23:046109

These files were contributed by A Proddutur.

The NEURON simulator is freely available from


This model was originally run under and requires microsoft windows.
The mod files need to be compiled with mknrndll.  To run
double click either

IClamp 50% gaps 30 SYNAPSES  tonicspill -74mV_0.6nA.hoc

which in less than 10 minutes should produce figures like these
(zoomed in on the first 150 ms)


PPSTIM 50% gaps 30 SYNAPSES  tonicspill -74mV.hoc

in Windows Explorer (after NEURON is installed).

2022-05: Updated MOD files to contain valid C++ and be compatible with
         the upcoming versions 8.2 and 9.0 of NEURON.
2022-09: Update MOD files to avoid declaring variables and functions with the same name.