Ait Ouares K, Filipis L, Tzilivaki A, Poirazi P, Canepari M (2019) Two distinct sets of Ca2+ and K+ channels are activated at different membrane potentials by the climbing fibre synaptic potential in Purkinje neuron dendrites. J Neurosci

This model was contributed by Luiza Filipis and reproduces Cell1 of Figure 9 on paper. If you need more help than the below in running the model please consult the web page: https://senselab.med.yale.edu/ModelDB/NEURON_DwnldGuide.cshtml

MSWIN
-----

Run mknrndll, cd to the expanded directory and click on the make nrnmech.dll button. Under windows explorer double click on the mosinitD.hoc, mosinitH.hoc or mosinitI.hoc file to see the result for the Depolarised, Hyperpolarised or Intermediate state respectively.

LINUX/UNIX
----------

Run nrnivmodl in the expanded archive folder. Then type nrngui mosinitD.hoc, mosinitH.hoc or mosinitI.hoc file to see the result for the Depolarised, Hyperpolarised or Intermediate state respectively.

MAC OS X
--------

Drag and drop the expanded folder onto the mknrndll icon. Drag and drop the mosinitD.hoc, mosinitH.hoc or mosinitI.hoc file onto the nrngui icon to see the result for the Depolarised, Hyperpolarised or Intermediate state respectively.

Depolarized:

Hyperpolarized:

Intermediate:

Changelog
----------

* cdp5.mod is updated due to issue mentioned in https://github.com/neuronsimulator/nrn/pull/1955. CONSTANT block has no effect in the initialization of ion variables.