This is the README file for the model associated with the paper:

Denizot, A., Arizono, M., Nägerl, V., Soula, H., Berry, H. (2019). Simulation of calcium signaling in fine astrocytic processes: effect of spatial properties on spontaneous activity. 


We present here 4 different implementations of the model, described below.


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##### Gillespie #####
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This model corresponds to the Gillespie implementation of the model. It has been developed in python. This model has been used in Figure 2.


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######## ODE ########
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This model corresponds to ODE model presented in Fig2 of the paper. It requires XPPAUT software, which is freely available at http://www.math.pitt.edu/~bard/xpp/xpp.html


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### Particle-based ###
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This model corresponds to the particle-based implementation of the model. It has been developed in C. This is the model used in Figures 2 to 5 of the paper.


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##### STEPS #####
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This model corresponds to the GCaMP6s model presented in Fig6 of the paper. It has been developed in python and requires STEPS software, which is freely available at http://steps.sourceforge.net/STEPS/default.php



Contact:
audrey.denizot@inria.fr