# Codes that reproduce the computational model of Bilash et al manuscript. Enter `_codes` directory. ## mechanisms This directory contains all .mod files that are used in the hoc neuronal models. ## poisson inputs Python script that generates theta-filtered poisson inputs. ## Python scripts ### `{cellname}_cell.py`: validation of the {cell_name} cell ### `{cellname}_synapses.py`: validation of the {cell_name} synapses `{cellname}` can take the values: - pyramidal - cck - olm - vipcr - vipcck ### The rest files are described below: #### analysis_canonical_circuit.py Analysis script that analyzes the voltage traces of the single presynaptic spike simulation. #### analysis_interneurons_synapses.py Script that analyses the outputs from `{interneuron_name}_synapses.py` scritps. #### analysis_poisson_inputs.py Analysis script that analyzes the voltage traces of the poisson inputs simulation. #### analysis_single_cell.py Analysis script that analyzes the voltage traces of the single cell experiment. #### canonical_circuit.py Script that simulates the canonical circuit. Stimulation of all EC at t=700ms. #### canonical_circuit_poisson_inputs.py Script that simulates the canonical circuit. Stimulation of all EC with theta-filtered poisson inputs. #### canonical_ccsv_files_.py Transform the output in csv files to import them on GraphPad. #### cell_models.py Classes of all neuronal models used here. #### opt.py Plot functions and NEURON initialization function. #### plots_poisson_inputs.py Plotting of poisson input experiments. #### soma_spiking_analysis.py Somatic firing and ISI for the poisson input experiment. #### synaptic_metrics.py Function that calculate all synaptic metrics, such as rise time and decay time. Author: Spiros Chavlis, PhD (schavlis [AT] imbb [DOT] forth [DOT] gr)