The following explanation has been generated automatically by AI and may contain errors.
# Biological Basis of the Computational Model The provided code models the phase distribution in a network of neurons, incorporating a level of randomness that reflects biological variability in neuronal systems. Key aspects of the code relevant to the biological modeling include: ## Randomness in Phase Distribution - **Sigma of Phase Distribution (`sigR`)**: The variable `sigR` in the code represents different levels of randomness in the phase distribution of neuronal firing. In a biological context, this could model the variability in synaptic inputs, heterogeneity in neuronal properties, or variability due to network connectivity. A `sigR` value of 0 implies no variability (perfect phase alignment across neurons), while a `sigR` value of 1 implies maximal randomness, modeling a realistic scenario where neurons exhibit a broad range of firing phases. ## Neural Population - **Number of Neurons (`NN`)**: The variable `NN` sets the total count of neurons in the simulation (1150 neurons in this case), which can be seen as a representation of a neural population. This aligns with biological concepts where populations of neurons operate with varying phases and amplitudes of oscillations. ## Amplitude and Frequency - **Amplitude (`Af`) and Frequency (`f`)**: The amplitude (`Af=1`) and frequency (`f=5 Hz`) are parameters for the oscillatory input, which mimic neuronal oscillation or rhythmic activity observed in cortical networks. These values reflect the rhythmic firing patterns that are characteristic of many neural circuits, especially those involved in processes such as sensory processing, motor control, and cognitive functions. ## Phase Distribution - **Phase (`phi`)**: The computed phase for each neuron reflects differences in neuronal firing. This mirrors how neurons in the brain can be entrained to oscillate with a particular phase relative to a network rhythm, yet still maintain some individuality due to intrinsic heterogeneity or disparate network influences. ## Visualization - **Histograms and Plotting**: The generated histograms and visualizations provide insights into how phase variability affects the synchronicity of neuronal populations, which is crucial for understanding phenomena like oscillatory synchrony, coherence in brain rhythms, and the effects of desynchronized activity observed in certain neuropathological conditions. In summary, the code aims to emulate the heterogeneity and variability in the synchronization of neuronal firing phases across a neural population, a fundamental aspect of how biological neural networks operate. This simulation can provide insight into how different levels of randomness in neuron synchronization influence network behavior, mirroring the complex dynamics found in the brain.