"The present study examines the biophysical properties and functional implications of Ih in hippocampal area CA3 interneurons with somata in strata radiatum and lacunosum-moleculare.... The functional consequences of Ih were examined with regard to temporal summation and impedance measurements. ... From impedance measurements, we found that Ih did not confer theta-band resonance, but flattened the impedance–frequency relations instead. ... Finally, a model of Ih was employed in computational analyses to confirm and elaborate upon the contributions of Ih to impedance and temporal summation."
Model Type: Neuron or other electrically excitable cell; Channel/Receptor
Region(s) or Organism(s): Hippocampus
Cell Type(s): Hippocampus CA3 stratum oriens lacunosum-moleculare interneuron; Hippocampus CA3 stratum radiatum lacunosum-moleculare interneuron
Currents: I h
Simulation Environment: MATLAB
References:
Anderson WD, Galván EJ, Mauna JC, Thiels E, Barrionuevo G. (2011). Properties and functional implications of I (h) in hippocampal area CA3 interneurons. Pflugers Archiv : European journal of physiology. 462 [PubMed]