This is a single cell model with variable intra and extra cellular ion concentrations for Na+, K+ and Cl- ions. This model also incorporates both the electrogenic and ionic concentration effects of the Na+/K+ pump. The program in this archive will run under CONTENT software to generate various bifurcation plots.
Model Type: Neuron or other electrically excitable cell
Cell Type(s): Neocortex L5/6 pyramidal GLU cell
Model Concept(s): Action Potentials
Simulation Environment: CONTENT
Implementer(s): Bazhenov, Maxim [Bazhenov at Salk.edu]
References:
Krishnan GP, Filatov G, Shilnikov A, Bazhenov M. (2015). Electrogenic properties of the Na?/K? ATPase control transitions between normal and pathological brain states. Journal of neurophysiology. 113 [PubMed]