Spikelet generation and AP initiation in a simplified pyr neuron (Michalikova et al. 2017) Fig 3


The article by Michalikova et al. (2017) explores the generation of spikelets in cortical pyramidal neurons. This package contains code for simulating the model with simplified morphology shown in Figs 3 and S2.

Model Type: Neuron or other electrically excitable cell; Axon

Currents: I Na,t

Model Concept(s): Action Potentials; Electrotonus; Action Potential Initiation; Axonal Action Potentials

Simulation Environment: NEURON; Python

Implementer(s): Michalikova, Martina [tinka.michalikova at gmail.com]

References:

Michalikova M, Remme MW, Kempter R. (2017). Spikelets in Pyramidal Neurons: Action Potentials Initiated in the Axon Initial Segment That Do Not Activate the Soma. PLoS computational biology. 13 [PubMed]


This website requires cookies and limited processing of your personal data in order to function. By continuing to browse or otherwise use this site, you are agreeing to this use. See our Privacy policy and how to cite and terms of use.