CA3 hippocampal pyramidal neuron with voltage-clamp intrinsic conductance data (Traub et al 1991)

This is a third-party implementation of the model from Traub et al 1991; as of 2021, Google Scholar reports about 780 citation articles. This model was one of the first biophysical models of a hippocampal pyramidal neuron with realistic conductances and the conductance equations have been used as a starting point for many models since, particularly those examining calcium dynamics and bursting.

Model Type: Dendrite

Region(s) or Organism(s): Hippocampus

Cell Type(s): Hippocampus CA3 pyramidal GLU cell

Currents: I Calcium; I A; I K,Ca; I Sodium; I K

Model Concept(s): Active Dendrites

Simulation Environment: NEURON

Implementer(s): Conde, James; Dewell, Richard Burkett [dewell at bcm.edu]; Gabbiani, F

References:

Traub RD, Wong RK, Miles R, Michelson H. (1991). A model of a CA3 hippocampal pyramidal neuron incorporating voltage-clamp data on intrinsic conductances. Journal of neurophysiology. 66 [PubMed]