The authors investigated the hypothesis that 20-80Hz neuronal (gamma) oscillations can emerge in sparsely connected network models of GABAergic fast-spiking interneurons. They explore model NN synchronization and compare their results to anatomical and electrophysiological data from hippocampal fast spiking interneurons.
Model Type: Realistic Network
Region(s) or Organism(s): Hippocampus
Cell Type(s): Abstract Wang-Buzsaki neuron
Receptors: GabaA
Model Concept(s): Activity Patterns; Oscillations; Synchronization
Simulation Environment: NEURON
Implementer(s): Hines, Michael [Michael.Hines at Yale.edu]; Lytton, William [bill.lytton at downstate.edu]
References:
Wang XJ, Buzsáki G. (1996). Gamma oscillation by synaptic inhibition in a hippocampal interneuronal network model. The Journal of neuroscience : the official journal of the Society for Neuroscience. 16 [PubMed]