This package simulates synaptic background activity similar to in vivo measurements using a model of fluctuating synaptic conductances, and compares the simulations with analytic estimates. The steady-state membrane potential (Vm) distribution is calculated numerically and compared with the "extended" analytic expression provided in the reference (see this paper for details).
Model Type: Synapse
Cell Type(s): Neocortex L5/6 pyramidal GLU cell
Model Concept(s): Simplified Models; Synaptic noise
Simulation Environment: NEURON
Implementer(s): Destexhe, Alain [Destexhe at iaf.cnrs-gif.fr]
References:
Rudolph M, Destexhe A. (2005). An extended analytic expression for the membrane potential distribution of conductance-based synaptic noise. Neural computation. 17 [PubMed]