Rejuvenation model of dopamine neuron (Chan et al. 2007)

Model files for the paper C. Savio Chan, et al. 'Rejuvenation' protects neurons in mouse models of Parkinson's disease, Nature 447, 1081-1086(28 June 2007).

Model Type: Neuron or other electrically excitable cell

Currents: I Na,t; I K; I h; I K,Ca; I Sodium; I Calcium; I Potassium

Genes: Cav1.3 CACNA1D

Model Concept(s): Simplified Models; Action Potentials; Parkinson's

Simulation Environment: NEURON

Implementer(s): Held, Joshua [j-held at northwestern.edu]

References:

Chan CS et al. (2007). 'Rejuvenation' protects neurons in mouse models of Parkinson's disease. Nature. 447 [PubMed]