Conduction in uniform myelinated axons (Moore et al 1978)

Examines the relative sensitivity of the velocity of impulse propagation to changes in nodal and internodal parameters.

Model Type: Axon

Cell Type(s): Myelinated neuron

Currents: I Na,t; I K

Model Concept(s): Axonal Action Potentials; Multiple sclerosis

Simulation Environment: NEURON

Implementer(s): Hines, Michael [Michael.Hines at Yale.edu]

References:

Moore JW, Joyner RW, Brill MH, Waxman SD, Najar-Joa M. (1978). Simulations of conduction in uniform myelinated fibers. Relative sensitivity to changes in nodal and internodal parameters. Biophysical journal. 21 [PubMed]