Kim M et al. (2011). Colocalization of protein kinase A with adenylyl cyclase enhances protein kinase A activity during induction of long-lasting long-term-potentiation. PLoS computational biology. 7 [PubMed]

See more from authors: Kim M · Park AJ · Havekes R · Chay A · Guercio LA · Oliveira RF · Abel T · Blackwell KT

References and models cited by this paper

Ajay SM, Bhalla US. (2007). A propagating ERKII switch forms zones of elevated dendritic activation correlated with plasticity. HFSP journal. 1 [PubMed]

Augustine GJ, Santamaria F, Tanaka K. (2003). Local calcium signaling in neurons. Neuron. 40 [PubMed]

Bagal AA, Kao JP, Tang CM, Thompson SM. (2005). Long-term potentiation of exogenous glutamate responses at single dendritic spines. Proceedings of the National Academy of Sciences of the United States of America. 102 [PubMed]

Baillie GS, Scott JD, Houslay MD. (2005). Compartmentalisation of phosphodiesterases and protein kinase A: opposites attract. FEBS letters. 579 [PubMed]

Balijepalli RC, Foell JD, Hall DD, Hell JW, Kamp TJ. (2006). Localization of cardiac L-type Ca(2+) channels to a caveolar macromolecular signaling complex is required for beta(2)-adrenergic regulation. Proceedings of the National Academy of Sciences of the United States of America. 103 [PubMed]

Banke TG et al. (2000). Control of GluR1 AMPA receptor function by cAMP-dependent protein kinase. The Journal of neuroscience : the official journal of the Society for Neuroscience. 20 [PubMed]

Bauman AL et al. (2006). Dynamic regulation of cAMP synthesis through anchored PKA-adenylyl cyclase V/VI complexes. Molecular cell. 23 [PubMed]

Blackwell KT. (2006). An efficient stochastic diffusion algorithm for modeling second messengers in dendrites and spines. Journal of neuroscience methods. 157 [PubMed]

Blitzer RD et al. (1998). Gating of CaMKII by cAMP-regulated protein phosphatase activity during LTP. Science (New York, N.Y.). 280 [PubMed]

Carr DW, Stofko-Hahn RE, Fraser ID, Cone RD, Scott JD. (1992). Localization of the cAMP-dependent protein kinase to the postsynaptic densities by A-kinase anchoring proteins. Characterization of AKAP 79. The Journal of biological chemistry. 267 [PubMed]

Citri A, Malenka RC. (2008). Synaptic plasticity: multiple forms, functions, and mechanisms. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 33 [PubMed]

Cooper DM. (2005). Compartmentalization of adenylate cyclase and cAMP signalling. Biochemical Society transactions. 33 [PubMed]

De Koninck P, Schulman H. (1998). Sensitivity of CaM kinase II to the frequency of Ca2+ oscillations. Science (New York, N.Y.). 279 [PubMed]

Dell'Acqua ML et al. (2006). Regulation of neuronal PKA signaling through AKAP targeting dynamics. European journal of cell biology. 85 [PubMed]

Dessauer CW. (2009). Adenylyl cyclase--A-kinase anchoring protein complexes: the next dimension in cAMP signaling. Molecular pharmacology. 76 [PubMed]

Efendiev R et al. (2010). AKAP79 interacts with multiple adenylyl cyclase (AC) isoforms and scaffolds AC5 and -6 to alpha-amino-3-hydroxyl-5-methyl-4-isoxazole-propionate (AMPA) receptors. The Journal of biological chemistry. 285 [PubMed]

Esteban JA et al. (2003). PKA phosphorylation of AMPA receptor subunits controls synaptic trafficking underlying plasticity. Nature neuroscience. 6 [PubMed]

Frey U, Huang YY, Kandel ER. (1993). Effects of cAMP simulate a late stage of LTP in hippocampal CA1 neurons. Science (New York, N.Y.). 260 [PubMed]

Frey U, Morris RG. (1997). Synaptic tagging and long-term potentiation. Nature. 385 [PubMed]

Gillespie DT. (2001). Approximate accelerated stochastic simulation of chemically reacting systems The Journal Of Chemical Physics. 115

Harris KM, Stevens JK. (1989). Dendritic spines of CA 1 pyramidal cells in the rat hippocampus: serial electron microscopy with reference to their biophysical characteristics. The Journal of neuroscience : the official journal of the Society for Neuroscience. 9 [PubMed]

Harrison JK, Hewlett GH, Gnegy ME. (1989). Regulation of calmodulin-sensitive adenylate cyclase by the stimulatory G-protein, Gs. The Journal of biological chemistry. 264 [PubMed]

Harvey CD, Yasuda R, Zhong H, Svoboda K. (2008). The spread of Ras activity triggered by activation of a single dendritic spine. Science (New York, N.Y.). 321 [PubMed]

Hattne J, Fange D, Elf J. (2005). Stochastic reaction-diffusion simulation with MesoRD. Bioinformatics (Oxford, England). 21 [PubMed]

Helmchen F, Imoto K, Sakmann B. (1996). Ca2+ buffering and action potential-evoked Ca2+ signaling in dendrites of pyramidal neurons. Biophysical journal. 70 [PubMed]

Holcman D, Korkotian E, Segal M. (2005). Calcium dynamics in dendritic spines, modeling and experiments. Cell calcium. 37 [PubMed]

Huang Q et al. (1992). Immunohistochemical localization of the D1 dopamine receptor in rat brain reveals its axonal transport, pre- and postsynaptic localization, and prevalence in the basal ganglia, limbic system, and thalamic reticular nucleus. Proceedings of the National Academy of Sciences of the United States of America. 89 [PubMed]

Huang T, McDonough CB, Abel T. (2006). Compartmentalized PKA signaling events are required for synaptic tagging and capture during hippocampal late-phase long-term potentiation. European journal of cell biology. 85 [PubMed]

Hudmon A et al. (2005). CaMKII tethers to L-type Ca2+ channels, establishing a local and dedicated integrator of Ca2+ signals for facilitation. The Journal of cell biology. 171 [PubMed]

Isaacson SA. (2009). The Reaction-Diffusion Master Equation as an Asymptotic Approximation of Diffusion to a Small Target SIAM J Appl Math. 70

Kaeser PS et al. (2008). RIM1alpha phosphorylation at serine-413 by protein kinase A is not required for presynaptic long-term plasticity or learning. Proceedings of the National Academy of Sciences of the United States of America. 105 [PubMed]

Kholodenko BN. (2009). Spatially distributed cell signalling. FEBS letters. 583 [PubMed]

Kim M, Huang T, Abel T, Blackwell KT. (2010). Temporal sensitivity of protein kinase a activation in late-phase long term potentiation. PLoS computational biology. 6 [PubMed]

Kim SA, Heinze KG, Waxham MN, Schwille P. (2004). Intracellular calmodulin availability accessed with two-photon cross-correlation. Proceedings of the National Academy of Sciences of the United States of America. 101 [PubMed]

Koh W, Blackwell KT. (2011). An accelerated algorithm for discrete stochastic simulation of reaction-diffusion systems using gradient-based diffusion and tau-leaping. The Journal of chemical physics. 134 [PubMed]

Kotaleski JH, Blackwell KT. (2010). Modelling the molecular mechanisms of synaptic plasticity using systems biology approaches. Nature reviews. Neuroscience. 11 [PubMed]

Lee HK, Barbarosie M, Kameyama K, Bear MF, Huganir RL. (2000). Regulation of distinct AMPA receptor phosphorylation sites during bidirectional synaptic plasticity. Nature. 405 [PubMed]

Lee HK, Takamiya K, He K, Song L, Huganir RL. (2010). Specific roles of AMPA receptor subunit GluR1 (GluA1) phosphorylation sites in regulating synaptic plasticity in the CA1 region of hippocampus. Journal of neurophysiology. 103 [PubMed]

Lee TW, Seifert R, Guan X, Kobilka BK. (1999). Restricting the mobility of Gs alpha: impact on receptor and effector coupling. Biochemistry. 38 [PubMed]

Lemon N, Manahan-Vaughan D. (2006). Dopamine D1/D5 receptors gate the acquisition of novel information through hippocampal long-term potentiation and long-term depression. The Journal of neuroscience : the official journal of the Society for Neuroscience. 26 [PubMed]

Lörincz A, Rózsa B, Katona G, Vizi ES, Tamás G. (2007). Differential distribution of NCX1 contributes to spine-dendrite compartmentalization in CA1 pyramidal cells. Proceedings of the National Academy of Sciences of the United States of America. 104 [PubMed]

MacKenzie SJ et al. (2002). Long PDE4 cAMP specific phosphodiesterases are activated by protein kinase A-mediated phosphorylation of a single serine residue in Upstream Conserved Region 1 (UCR1). British journal of pharmacology. 136 [PubMed]

Majewska A, Brown E, Ross J, Yuste R. (2000). Mechanisms of calcium decay kinetics in hippocampal spines: role of spine calcium pumps and calcium diffusion through the spine neck in biochemical compartmentalization. The Journal of neuroscience : the official journal of the Society for Neuroscience. 20 [PubMed]

Mammen AL, Kameyama K, Roche KW, Huganir RL. (1997). Phosphorylation of the alpha-amino-3-hydroxy-5-methylisoxazole4-propionic acid receptor GluR1 subunit by calcium/calmodulin-dependent kinase II. The Journal of biological chemistry. 272 [PubMed]

Markram H, Roth A, Helmchen F. (1998). Competitive calcium binding: implications for dendritic calcium signaling. Journal of computational neuroscience. 5 [PubMed]

Mills LR et al. (1994). N-type Ca2+ channels are located on somata, dendrites, and a subpopulation of dendritic spines on live hippocampal pyramidal neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. 14 [PubMed]

Mullasseril P, Dosemeci A, Lisman JE, Griffith LC. (2007). A structural mechanism for maintaining the 'on-state' of the CaMKII memory switch in the post-synaptic density. Journal of neurochemistry. 103 [PubMed]

Müller A et al. (2005). Endogenous Ca2+ buffer concentration and Ca2+ microdomains in hippocampal neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. 25 [PubMed]

Neves SR et al. (2008). Cell shape and negative links in regulatory motifs together control spatial information flow in signaling networks. Cell. 133 [PubMed]

Nguyen PV, Woo NH. (2003). Regulation of hippocampal synaptic plasticity by cyclic AMP-dependent protein kinases. Progress in neurobiology. 71 [PubMed]

Nie T, McDonough CB, Huang T, Nguyen PV, Abel T. (2007). Genetic disruption of protein kinase A anchoring reveals a role for compartmentalized kinase signaling in theta-burst long-term potentiation and spatial memory. The Journal of neuroscience : the official journal of the Society for Neuroscience. 27 [PubMed]

Noguchi J, Matsuzaki M, Ellis-Davies GC, Kasai H. (2005). Spine-neck geometry determines NMDA receptor-dependent Ca2+ signaling in dendrites. Neuron. 46 [PubMed]

Oliveira RF et al. (2010). The role of type 4 phosphodiesterases in generating microdomains of cAMP: large scale stochastic simulations. PloS one. 5 [PubMed]

Pelkey KA, Topolnik L, Yuan XQ, Lacaille JC, McBain CJ. (2008). State-dependent cAMP sensitivity of presynaptic function underlies metaplasticity in a hippocampal feedforward inhibitory circuit. Neuron. 60 [PubMed]

Piggott LA, Bauman AL, Scott JD, Dessauer CW. (2008). The A-kinase anchoring protein Yotiao binds and regulates adenylyl cyclase in brain. Proceedings of the National Academy of Sciences of the United States of America. 105 [PubMed]

Quintana AR, Wang D, Forbes JE, Waxham MN. (2005). Kinetics of calmodulin binding to calcineurin. Biochemical and biophysical research communications. 334 [PubMed]

Rice ME, Cragg SJ. (2004). Nicotine amplifies reward-related dopamine signals in striatum. Nature neuroscience. 7 [PubMed]

Roche KW, O'Brien RJ, Mammen AL, Bernhardt J, Huganir RL. (1996). Characterization of multiple phosphorylation sites on the AMPA receptor GluR1 subunit. Neuron. 16 [PubMed]

Sabatini BL, Oertner TG, Svoboda K. (2002). The life cycle of Ca(2+) ions in dendritic spines. Neuron. 33 [PubMed]

Scheuss V, Yasuda R, Sobczyk A, Svoboda K. (2006). Nonlinear [Ca2+] signaling in dendrites and spines caused by activity-dependent depression of Ca2+ extrusion. The Journal of neuroscience : the official journal of the Society for Neuroscience. 26 [PubMed]

Terrin A et al. (2006). PGE(1) stimulation of HEK293 cells generates multiple contiguous domains with different [cAMP]: role of compartmentalized phosphodiesterases. The Journal of cell biology. 175 [PubMed]

Tostevin F, ten Wolde PR, Howard M. (2007). Fundamental limits to position determination by concentration gradients. PLoS computational biology. 3 [PubMed]

Tunquist BJ et al. (2008). Loss of AKAP150 perturbs distinct neuronal processes in mice. Proceedings of the National Academy of Sciences of the United States of America. 105 [PubMed]

Vecsey CG et al. (2009). Sleep deprivation impairs cAMP signalling in the hippocampus. Nature. 461 [PubMed]

Verney C et al. (1985). Morphological evidence for a dopaminergic terminal field in the hippocampal formation of young and adult rat. Neuroscience. 14 [PubMed]

Vincent P, Gervasi N, Zhang J. (2008). Real-time monitoring of cyclic nucleotide signaling in neurons using genetically encoded FRET probes. Brain cell biology. 36 [PubMed]

Wang H, Storm DR. (2003). Calmodulin-regulated adenylyl cyclases: cross-talk and plasticity in the central nervous system. Molecular pharmacology. 63 [PubMed]

Weisenhaus M et al. (2010). Mutations in AKAP5 disrupt dendritic signaling complexes and lead to electrophysiological and behavioral phenotypes in mice. PloS one. 5 [PubMed]

Wong W, Scott JD. (2004). AKAP signalling complexes: focal points in space and time. Nature reviews. Molecular cell biology. 5 [PubMed]

Young JZ, Isiegas C, Abel T, Nguyen PV. (2006). Metaplasticity of the late-phase of long-term potentiation: a critical role for protein kinase A in synaptic tagging. The European journal of neuroscience. 23 [PubMed]

Yuste R, Majewska A, Cash SS, Denk W. (1999). Mechanisms of calcium influx into hippocampal spines: heterogeneity among spines, coincidence detection by NMDA receptors, and optical quantal analysis. The Journal of neuroscience : the official journal of the Society for Neuroscience. 19 [PubMed]

Zaccolo M. (2006). Phosphodiesterases and compartmentalized cAMP signalling in the heart. European journal of cell biology. 85 [PubMed]

Zawadzki KM, Taylor SS. (2004). cAMP-dependent protein kinase regulatory subunit type IIbeta: active site mutations define an isoform-specific network for allosteric signaling by cAMP. The Journal of biological chemistry. 279 [PubMed]

Zhong H et al. (2009). Subcellular dynamics of type II PKA in neurons. Neuron. 62 [PubMed]

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