Holmes WR. (2000). Models of calmodulin trapping and CaM kinase II activation in a dendritic spine. Journal of computational neuroscience. 8 [PubMed]

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References and models cited by this paper

Barnes GN, Slevin JT, Vanaman TC. (1995). Rat brain protein phosphatase 2A: an enzyme that may regulate autophosphorylated protein kinases. Journal of neurochemistry. 64 [PubMed]

Barria A, Muller D, Derkach V, Griffith LC, Soderling TR. (1997). Regulatory phosphorylation of AMPA-type glutamate receptors by CaM-KII during long-term potentiation. Science (New York, N.Y.). 276 [PubMed]

Bekkers JM, Stevens CF. (1989). NMDA and non-NMDA receptors are co-localized at individual excitatory synapses in cultured rat hippocampus. Nature. 341 [PubMed]

Bliss TV, Collingridge GL. (1993). A synaptic model of memory: long-term potentiation in the hippocampus. Nature. 361 [PubMed]

Blitzer RD et al. (1998). Gating of CaMKII by cAMP-regulated protein phosphatase activity during LTP. Science (New York, N.Y.). 280 [PubMed]

Brickey DA et al. (1994). Mutational analysis of the autoinhibitory domain of calmodulin kinase II. The Journal of biological chemistry. 269 [PubMed]

Burger D, Stein EA, Cox JA. (1983). Free energy coupling in the interactions between Ca2+, calmodulin, and phosphorylase kinase. The Journal of biological chemistry. 258 [PubMed]

Colbran RJ. (1993). Inactivation of Ca2+/calmodulin-dependent protein kinase II by basal autophosphorylation. The Journal of biological chemistry. 268 [PubMed]

Comte M, Cox JH, Mamar-bachi A, Milos M, Schaer J-J. (1988). Cation binding to calmodulin and relation to function Calcium and Calcium Binding Proteins.

Coomber C. (1998). Current theories of neuronal information processing performed by Ca2+/calmodulin-dependent protein kinase II with support and insights from computer modelling and simulation. Computers & chemistry. 22 [PubMed]

Coussens CM, Teyler TJ. (1996). Protein kinase and phosphatase activity regulate the form of synaptic plasticity expressed. Synapse (New York, N.Y.). 24 [PubMed]

Cox JA, Burger D, Comte M, Stein EA. (1984). Sequential conformational changes in calmodulin upon binding of calcium Biochemistry. 23

Crouch TH, Klee CB. (1980). Positive cooperative binding of calcium to bovine brain calmodulin. Biochemistry. 19 [PubMed]

Cummings JA, Mulkey RM, Nicoll RA, Malenka RC. (1996). Ca2+ signaling requirements for long-term depression in the hippocampus. Neuron. 16 [PubMed]

De Koninck P, Schulman H. (1998). Sensitivity of CaM kinase II to the frequency of Ca2+ oscillations. Science (New York, N.Y.). 279 [PubMed]

Desmond NL, Levy WB. (1985). Granule cell dendritic spine density in the rat hippocampus varies with spine shape and location. Neuroscience letters. 54 [PubMed]

Dosemeci A, Albers RW. (1996). A mechanism for synaptic frequency detection through autophosphorylation of CaM kinase II. Biophysical journal. 70 [PubMed]

Dosemeci A, Gollop N, Jaffe H. (1994). Identification of a major autophosphorylation site on postsynaptic density-associated Ca2+/calmodulin-dependent protein kinase. J Biol Chem. 269

Edwards FR, Walmsley B, Tracey DJ. (1988). Nonuniform release probabilities underlie quantal synaptic transmission at a mammalian excitatory central synapse. J Neurophysiol. 60

Frey U, Morris RG. (1997). Synaptic tagging and long-term potentiation. Nature. 385 [PubMed]

Fukunaga K, Muller D, Miyamoto E. (1996). CaM kinase II in long-term potentiation. Neurochemistry international. 28 [PubMed]

Fukunaga K, Stoppini L, Miyamoto E, Muller D. (1993). Long-term potentiation is associated with an increased activity of Ca2+/calmodulin-dependent protein kinase II. The Journal of biological chemistry. 268 [PubMed]

Gregori L, Gillevet PM, Doan P, Chau V. (1985). Mechanism of enzyme regulation by calmodulin and Ca2+. Current topics in cellular regulation. 27 [PubMed]

Hanse E, Gustafsson B. (1992). Long-term Potentiation and Field EPSPs in the Lateral and Medial Perforant Paths in the Dentate Gyrus In Vitro: a Comparison. The European journal of neuroscience. 4 [PubMed]

Hansel C, Artola A, Singer W. (1996). Different threshold levels of postsynaptic [Ca2+]i have to be reached to induce LTP and LTD in neocortical pyramidal cells. Journal of physiology, Paris. 90 [PubMed]

Hanson PI, Meyer T, Stryer L, Schulman H. (1994). Dual role of calmodulin in autophosphorylation of multifunctional CaM kinase may underlie decoding of calcium signals. Neuron. 12 [PubMed]

Hanson PI, Schulman H. (1992). Inhibitory autophosphorylation of multifunctional Ca2+/calmodulin-dependent protein kinase analyzed by site-directed mutagenesis. The Journal of biological chemistry. 267 [PubMed]

Hessler NA, Shirke AM, Malinow R. (1993). The probability of transmitter release at a mammalian central synapse. Nature. 366 [PubMed]

Holmes WR. (1990). Is the function of dendritic spines to concentrate calcium? Brain research. 519 [PubMed]

Holmes WR. (1995). Modeling the effect of glutamate diffusion and uptake on NMDA and non-NMDA receptor saturation. Biophysical journal. 69 [PubMed]

Holmes WR, Levy WB. (1990). Insights into associative long-term potentiation from computational models of NMDA receptor-mediated calcium influx and intracellular calcium concentration changes. Journal of neurophysiology. 63 [PubMed]

Holmes WR, Levy WB. (1997). Quantifying the role of inhibition in associative long-term potentiation in dentate granule cells with computational models. Journal of neurophysiology. 78 [PubMed]

Kakiuchi S et al. (1982). Quantitative determinations of calmodulin in the supernatant and particulate fractions of mammalian tissues. Journal of biochemistry. 92 [PubMed]

Kelly PT, McGuinness TL, Greengard P. (1984). Evidence that the major postsynaptic density protein is a component of a Ca2+/calmodulin-dependent protein kinase. Proceedings of the National Academy of Sciences of the United States of America. 81 [PubMed]

Kennedy MB, Bennett MK, Erondu NE. (1983). Biochemical and immunochemical evidence that the "major postsynaptic density protein" is a subunit of a calmodulin-dependent protein kinase. Proceedings of the National Academy of Sciences of the United States of America. 80 [PubMed]

Klee CB. (1988). Interaction of calmodulin with Ca2C and target proteins Calmodulin.

Kretsinger RH. (1981). Mechanisms of selective signalling by calcium Neurosci Res Prog Bull. 19

Linse S, Forsén S. (1995). Determinants that govern high-affinity calcium binding. Advances in second messenger and phosphoprotein research. 30 [PubMed]

Linse S, Helmersson A, Forsén S. (1991). Calcium binding to calmodulin and its globular domains. The Journal of biological chemistry. 266 [PubMed]

Lisman J. (1989). A mechanism for the Hebb and the anti-Hebb processes underlying learning and memory. Proceedings of the National Academy of Sciences of the United States of America. 86 [PubMed]

Lisman J. (1994). The CaM kinase II hypothesis for the storage of synaptic memory. Trends in neurosciences. 17 [PubMed]

Lisman J, Malenka RC, Nicoll RA, Malinow R. (1997). Learning mechanisms: the case for CaM-KII. Science (New York, N.Y.). 276 [PubMed]

Luby-Phelps K, Hori M, Phelps JM, Won D. (1995). Ca(2+)-regulated dynamic compartmentalization of calmodulin in living smooth muscle cells. The Journal of biological chemistry. 270 [PubMed]

Malenka RC. (1991). The role of postsynaptic calcium in the induction of long-term potentiation. Molecular neurobiology. 5 [PubMed]

Malenka RC, Nicoll RA. (1993). NMDA-receptor-dependent synaptic plasticity: multiple forms and mechanisms. Trends in neurosciences. 16 [PubMed]

Matsushita T, Moriyama S, Fukai T. (1995). Switching dynamics and the transient memory storage in a model enzyme network involving Ca2+/calmodulin-dependent protein kinase II in synapses. Biological cybernetics. 72 [PubMed]

Mayer ML, Westbrook GL, Guthrie PB. (1984). Voltage-dependent block by Mg2+ of NMDA responses in spinal cord neurones. Nature. 309 [PubMed]

Mayford M, Wang J, Kandel ER, O'Dell TJ. (1995). CaMKII regulates the frequency-response function of hippocampal synapses for the production of both LTD and LTP. Cell. 81 [PubMed]

Meyer T, Hanson PI, Stryer L, Schulman H. (1992). Calmodulin trapping by calcium-calmodulin-dependent protein kinase. Science (New York, N.Y.). 256 [PubMed]

Miller SG, Kennedy MB. (1986). Regulation of brain type II Ca2+/calmodulin-dependent protein kinase by autophosphorylation: a Ca2+-triggered molecular switch. Cell. 44 [PubMed]

Miller SG, Patton BL, Kennedy MB. (1988). Sequences of autophosphorylation sites in neuronal type II CaM kinase that control Ca2(+)-independent activity. Neuron. 1 [PubMed]

Mukherji S, Soderling TR. (1994). Regulation of Ca2+/calmodulin-dependent protein kinase II by inter- and intrasubunit-catalyzed autophosphorylations. The Journal of biological chemistry. 269 [PubMed]

Ouyang Y, Kantor D, Harris KM, Schuman EM, Kennedy MB. (1997). Visualization of the distribution of autophosphorylated calcium/calmodulin-dependent protein kinase II after tetanic stimulation in the CA1 area of the hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience. 17 [PubMed]

Patton BL, Miller SG, Kennedy MB. (1990). Activation of type II calcium/calmodulin-dependent protein kinase by Ca2+/calmodulin is inhibited by autophosphorylation of threonine within the calmodulin-binding domain. The Journal of biological chemistry. 265 [PubMed]

Rosenmund C, Clements JD, Westbrook GL. (1993). Nonuniform probability of glutamate release at a hippocampal synapse. Science (New York, N.Y.). 262 [PubMed]

Sather W, Dieudonné S, MacDonald JF, Ascher P. (1992). Activation and desensitization of N-methyl-D-aspartate receptors in nucleated outside-out patches from mouse neurones. The Journal of physiology. 450 [PubMed]

Schulman H. (1993). The multifunctional Ca2+/calmodulin-dependent protein kinases. Current opinion in cell biology. 5 [PubMed]

Schulman H, Michelson S. (1994). CaM kinase: A model for its activation and dynamics J Theor Biol. 171

Silver RA, Traynelis SF, Cull-Candy SG. (1992). Rapid-time-course miniature and evoked excitatory currents at cerebellar synapses in situ. Nature. 355 [PubMed]

Soderling TR. (1993). Calcium/calmodulin-dependent protein kinase II: role in learning and memory. Molecular and cellular biochemistry. 127-128 [PubMed]

Staley KJ, Mody I. (1991). Integrity of perforant path fibers and the frequency of action potential independent excitatory and inhibitory synaptic events in dentate gyrus granule cells. Synapse (New York, N.Y.). 9 [PubMed]

Stemmer PM, Klee CB. (1994). Dual calcium ion regulation of calcineurin by calmodulin and calcineurin B. Biochemistry. 33 [PubMed]

Strack S, Barban MA, Wadzinski BE, Colbran RJ. (1997). Differential inactivation of postsynaptic density-associated and soluble Ca2+/calmodulin-dependent protein kinase II by protein phosphatases 1 and 2A. Journal of neurochemistry. 68 [PubMed]

Strack S, Choi S, Lovinger DM, Colbran RJ. (1997). Translocation of autophosphorylated calcium/calmodulin-dependent protein kinase II to the postsynaptic density. The Journal of biological chemistry. 272 [PubMed]

Stull JT. (1988). Myosin light chain kinases and caldesmon: biochemical properties and roles in skeletal and smooth muscle contractions Calmodulin.

Suzuki T, Okumura-Noji K, Tanaka R, Tada T. (1994). Rapid translocation of cytosolic Ca2+/calmodulin-dependent protein kinase II into postsynaptic density after decapitation. Journal of neurochemistry. 63 [PubMed]

Wang JH, Sharma RK, Mooibroek M. (1988). Calmodulin-stimulated cyclic nucleotide phosphodiesterase isozymes Calmodulin.

White G, Levy WB, Steward O. (1988). Evidence that associative interactions between synapses during the induction of long-term potentiation occur within local dendritic domains. Proceedings of the National Academy of Sciences of the United States of America. 85 [PubMed]

White G, Levy WB, Steward O. (1990). Spatial overlap between populations of synapses determines the extent of their associative interaction during the induction of long-term potentiation and depression. Journal of neurophysiology. 64 [PubMed]

Zador A, Koch C, Brown TH. (1990). Biophysical model of a Hebbian synapse. Proceedings of the National Academy of Sciences of the United States of America. 87 [PubMed]

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